UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


        Date of Report (Date of Earliest Event Reported): April 28, 2005


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


          DELAWARE                    1-11181                    94-2579751
(State or other jurisdiction        (Commission               (I.R.S. Employer
      of incorporation)             File Number)             Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

         |_|      Written   communications   pursuant  to  Rule  425  under  the
                  Securities Act (17 CFR 230.425)

         |_|      Soliciting material pursuant to Rule 14a-12 under the Exchange
                  Act (17 CFR 240.14a-12)

         |_|      Pre-commencement  communications  pursuant  to  Rule  14d-2(b)
                  under the Exchange Act (17 CFR 240.14d-2(B))

         |_|      Pre-commencement  communications  pursuant  to Rule  13e-4(c))
                  under the Exchange Act (17 CFR 240.13e-4c))





ITEM 2.02 - RESULTS OF OPERATION AND FINANCIAL CONDITION

            On  April  28,  2005,  we  issued  a press  release  announcing  our
financial results for the three-month period ended March 31, 2005. A copy of the
press release is attached hereto as Exhibit 99.1 and is  incorporated  herein by
reference.

            We will host a conference  call on April 28, 2005, at 11:00 a.m. EST
to review our financial results for the three-month period ended March 31, 2005.
The  call  may be  accessed  via a live  audio  web  cast  on our  web  site  at
www.proiris.com  or at  www.vcall.com,  or through a dial-in telephone number at
1-800-817-2743  (reference:  IRIS International conference call).  International
callers should dial 913-981-4915.

            A replay of the web cast of the conference  call will be archived in
the Investor Relations section of our web site at  www.proiris.com.  A telephone
replay will be available through May 5, 2005, at 1-888-203-1112; conference call
ID 5463293 (or 719-457-0820 for international callers).

            The  information in Item 2.02 of this Current Report on Form 8-K and
Exhibit 99.1 attached  hereto shall not be deemed to be "filed" for the purposes
of Section 18 of the Securities  Exchange Act of 1934 (the "Exchange  Act"),  or
otherwise subject to the liabilities of such section, nor shall such information
or  exhibit  be  deemed  incorporated  by  reference  in any  filing  under  the
Securities  Act of 1933 or the Exchange  Act,  except as shall be expressly  set
forth by specific reference in such a filing.

ITEM 9.01 - FINANCIAL STATEMENTS AND EXHIBITS

         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  EXHIBIT
                  NUMBER   DESCRIPTION
                  -------  -----------

                  99.1     Press Release dated April 28, 2005, published by IRIS
                           International, Inc.


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                           IRIS INTERNATIONAL, INC.



Date:    April 28, 2005              By:   /S/ MARTIN G. PARAVATO            
                                           ----------------------------------
                                               Martin G. Paravato
                                               Chief Financial Officer


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                                  EXHIBIT INDEX

EXHIBIT
NUMBER            DESCRIPTION
-------           -----------

99.1              Press  Release  dated  April  28,  2005,   published  by  IRIS
                  International, Inc.


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