UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


          Date of Report (Date of Earliest Event Reported): May 9, 2006


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


          DELAWARE                 1-11181                       94-2579751
(State or other jurisdiction    (Commission                   (I.R.S. Employer
     of incorporation)           File Number)                Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

         |_|      Written   communications   pursuant  to  Rule  425  under  the
                  Securities Act (17 CFR 230.425)

         |_|      Soliciting material pursuant to Rule 14a-12 under the Exchange
                  Act (17 CFR 240.14a-12)

         |_|      Pre-commencement  communications  pursuant  to  Rule  14d-2(b)
                  under the Exchange ct (17 CFR 240.14d-2(b))

         |_|      Pre-commencement  communications  pursuant  to Rule  13e-4(c))
                  under the Exchange Act (17 CFR 240.13e-4c))





ITEM 2.02 - RESULTS OF OPERATION AND FINANCIAL CONDITION

         On May 9, 2006,  we issued a press  release  announcing  our  financial
results for the first  quarter ended March 31, 2006. A copy of the press release
is attached hereto as Exhibit 99.1 and is incorporated herein by this reference.

         We hosted a conference  call on May 9, 2006, at 4:30 p.m.  Eastern time
to review our  financial  results for the first  quarter ended March 31, 2006. A
replay  of the call may be  accessed  on our web site at  www.proiris.com  or at
www.vcall.com for 30 days from the date of the broadcast. In addition, access to
a recording of the call will be available for seven days  following the call, by
dialing 1-888-203-1112  (719-457-0820 for international  callers). The pass code
I.D. is 3410282.

         The  information  in this Item 2.02 of this Current  Report on Form 8-K
and  Exhibit  99.1  attached  hereto  shall not be deemed to be "filed"  for the
purposes of Section 18 of the  Securities  Exchange  Act of 1934 (the  "Exchange
Act"), or otherwise  subject to the liabilities of such section,  nor shall such
information or exhibit be deemed  incorporated  by reference in any filing under
the Securities Act of 1933 or the Exchange Act, except as shall be expressly set
forth by specific reference in such a filing.


ITEM 9.01 - FINANCIAL STATEMENTS AND EXHIBITS

         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  EXHIBIT
                  NUMBER   DESCRIPTION
                  -------  -----------

                  99.1     Press  Release  dated May 9, 2006,  published by IRIS
                           International, Inc.


                                       2




                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                             IRIS INTERNATIONAL, INC.



Date:    May 9, 2006                By:      /s/ Martin G. Paravato
                                             -----------------------------------
                                             Martin G. Paravato
                                             Chief Financial Officer


                                       3



                                  EXHIBIT INDEX

EXHIBIT
NUMBER         DESCRIPTION
-------        -----------

99.1           Press Release dated May 9, 2006, published by IRIS International,
               Inc.


                                       4