UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

       Date of Report (Date of Earliest Event Reported): December 21, 2006


                            IRIS INTERNATIONAL, INC.
             (Exact name of registrant as specified in its charter)


          DELAWARE                    1-11181                    94-2579751
(State or other jurisdiction        (Commission               (I.R.S. Employer
     of incorporation)              File Number)             Identification No.)


                                9172 ETON AVENUE
                              CHATSWORTH, CA 91311
                (Address of Principal Executive Offices/Zip Code)


                                 (818) 709-1244
              (Registrant's telephone number, including area code)


         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

         |_|      Written   communications   pursuant  to  Rule  425  under  the
                  Securities Act (17 CFR 230.425)

         |_|      Soliciting material pursuant to Rule 14a-12 under the Exchange
                  Act (17 CFR 240.14a-12)

         |_|      Pre-commencement  communications  pursuant  to  Rule  14d-2(b)
                  under the Exchange ct (17 CFR 240.14d-2(b))

         |_|      Pre-commencement  communications  pursuant  to Rule  13e-4(c))
                  under the Exchange Act (17 CFR 240.13e-4c))





ITEM 5.02         DEPARTURE  OF DIRECTORS  OR  PRINCIPAL  OFFICERS;  ELECTION OF
                  DIRECTORS;  APPOINTMENT  OF PRINCIPAL  OFFICERS;  COMPENSATORY
                  ARRANGEMENTS OF CERTAIN OFFICERS.

(e)      AMENDMENT TO KEY EMPLOYEE  AGREEMENT WITH PRESIDENT AND CHIEF EXECUTIVE
         OFFICER

         On December  21, 2006 we entered  into an amendment to our existing Key
Employment  Agreement with our President and Chief Executive  Officer,  Cesar M.
Garcia  for the  purpose of  conforming  it to certain  provisions  of  Internal
Revenue Code Section 409A. The amendment prescribes a severance payment schedule
in the event of Mr. Garcia's  termination  without  "Cause," that seeks to avoid
the imposition of an excise tax as contemplated by Internal Revenue Code Section
409A, and provides for the automatic amendment of the agreement upon adoption of
final  regulations  such that  severance  payments  made under the agreement are
included in Mr.  Garcia's gross income at the time of actual payment and are not
included in his gross income and subject to the additional tax and interest that
would be required by Section 409A prior to such actual payment.

         Attached  as  Exhibit  10.1  is a  copy  of  the  amendment,  which  is
incorporated herein by reference.

ITEM 9.01.        FINANCIAL STATEMENTS AND EXHIBITS


         (c)      Exhibits.

                  The following exhibits are filed herewith:

                  EXHIBIT
                  NUMBER   DESCRIPTION
                  -------  -----------

                  10.1     IRIS  International,  Inc.  First  Amendment  to  Key
                           Employee   Agreement  for  Cesar  M.  Garcia,   dated
                           December 21, 2006.


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                           IRIS INTERNATIONAL, INC.



Date:    December 22, 2006          By:    /s/ Cesar M. Garcia
                                           -------------------------------------
                                           Cesar M. Garcia
                                           President and Chief Executive Officer


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