UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                  SCHEDULE 13D

                   Under the Securities Exchange Act of 1934

                                (Amendment No. 16)*



                          AEOLUS PHARMACEUTICALS, INC.
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                                (Name of Issuer)

                     Common Stock, par value $0.01 per share
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                         (Title of Class of Securities)

                                    00765G109
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                                 (CUSIP Number)

                                  Mary L. King
                         Xmark Opportunity Partners, LLC
                           90 Grove Street, Suite 201
                              Ridgefield, CT 06877
                                 (203) 588-2808
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                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                 March 30, 2009
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             (Date of Event which Requires Filing of this Statement)


If the filing person has previously  filed a statement on Schedule l3G to report
the  acquisition  that is the subject of this  Schedule  13D, and is filing this
schedule  because of Sections 240.13d-1(e), 240.13d-1(f)  or 240.13d-1(g), check
the following box. [  ]

Note:  Schedules  filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits.  See Section 240.13d-7 for other
parties to whom copies are to be sent.

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).




Cusip No.       00765G109
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1.  Names of Reporting Persons.  I.R.S. Identification Nos. of above persons
    (entities only):
               Xmark Opportunity Partners, LLC
               20-2052197
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2.  Check the Appropriate Box if a Member of a Group (See Instructions):
         (a)   Not
         (b)   Applicable
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3.  SEC Use Only

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4.  Source of Funds (See Instructions):  AF, WC
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5.  Check if Disclosure  of Legal Proceedings Is Required Pursuant to Items 2(d)
    or 2(e):               Not Applicable
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6.  Citizenship or Place of Organization:    United States

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    Number of                      7. Sole Voting Power:             22,996,154*
                                     -------------------------------------------
    Shares Beneficially            8. Shared Voting Power:
                                     -------------------------------------------
    Owned by
    Each Reporting                 9. Sole Dispositive Power:        21,996,154*
                                      ------------------------------------------
    Person With                    10. Shared Dispositive Power:
                                      ------------------------------------------
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11. Aggregate Amount Beneficially Owned by Each Reporting Person:   22,996,154*

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12. Check if  the Aggregate  Amount in  Row (11) Excludes  Certain  Shares  (See
    Instructions):         [ x ]*
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13. Percent of Class Represented by Amount in Row (11):   58.1%*
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14. Type of Reporting Person (See Instructions):  IA
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* Xmark Opportunity Partners, LLC ("Opportunity Partners") is the sole member of
the  investment  manager of Xmark  Opportunity  Fund,  L.P., a Delaware  limited
partnership  ("Opportunity  LP"),  and Xmark  Opportunity  Fund,  Ltd., a Cayman
Islands exempted company ("Opportunity Ltd"), and, as such, possesses sole power
to vote and direct the disposition of all securities of Aeolus  Pharmaceuticals,
Inc.,  a  Delaware  corporation  (the  "Company"),  held by  Opportunity  LP and
Opportunity  Ltd.  Opportunity  Partners is the  investment  manager of Xmark JV
Investment  Partners,  LLC, a Delaware limited liability company ("JV Partners",
and together with  Opportunity  LP and  Opportunity  Ltd, the "Funds"),  and, as
such,  possesses sole power to vote and direct the disposition of all securities
of the Company held by JV Partners.  Mitchell D. Kaye and David C. Cavalier, the
Co-Managing  Members of Xmark  Capital  Partners,  LLC, the  Managing  Member of
Opportunity  Partners,  share  voting and  investment  power with respect to all
securities  beneficially  owned  by  Opportunity  Partners.  Opportunity  LP and
Opportunity  Ltd,  together,  hold a majority  of the  membership  interests  in
Goodnow Capital, L.L.C., a Delaware limited liability company ("Goodnow"),  and,
as such,  Opportunity  Partners  possesses  sole  power to vote and  direct  the
disposition of all securities of the Company held by Goodnow.

As of March 30, 2009, Opportunity LP held (i) 5,041,469 common shares, $0.01 par
value per share (the "Common Shares"), of the Company,  which includes 1,276,435
Common Shares of the Company  owned by Goodnow,  (ii) warrants to purchase up to
660,000  Common  Shares of the Company at an  exercise  price of $0.28 per share
subject to certain adjustments, (iii) 7% senior convertible notes (collectively,
"Note 1"), in the aggregate principal amount of $300,000,  which are convertible
into 857,141  Common  Shares of the Company at a  conversion  price of $0.35 per
share subject to certain adjustments, (iv) warrants ("Warrant 1") to purchase up
to 600,000  Common Shares of the Company at an exercise price of $0.50 per share
subject to certain adjustments, and (v) warrants ("Warrant 2") to purchase up to
4,687,500  Common Shares of the Company at an exercise  price of $0.35 per share
subject to certain adjustments.  As of March 30, 2009,  Opportunity Ltd held (a)
10,251,003 Common Shares of the Company,  which includes 3,300,653 Common Shares
of the Company owned by Goodnow,  (b) warrants to purchase up to 990,000  Common
Shares of the Company at an exercise price of $0.28 per share subject to certain
adjustments,  (c) 7%  senior  convertible  notes  (together  with  Note  1,  the
"Notes"),  in the aggregate principal amount of $700,000,  which are convertible
into 1,999,998  Common Shares of the Company at a conversion  price of $0.35 per
share subject to certain adjustments,  (d) warrants ("Warrant 3") to purchase up
to  1,400,000  Common  Shares of the Company at an  exercise  price of $0.50 per
share  subject  to  certain  adjustments,  and (e)  warrants  ("Warrant  4", and
together with Warrant 1, Warrant 2 and Warrant 3, the "Warrants") to purchase up
to  8,705,357  Common  Shares of the Company at an  exercise  price of $0.35 per
share subject to certain adjustments. As of March 30, 2009, JV Partners held (1)
1,023,731  Common  Shares of the  Company  and (2)  warrants  to  purchase up to
500,000  Common  Shares of the Company at an  exercise  price of $0.28 per share
subject to certain adjustments.




All of the Notes and the Warrants contain an issuance limitation prohibiting the
holder from  converting or exercising,  as the case may be, those  securities to
the extent that after giving effect to such  conversion or exercise,  the holder
would  beneficially own more than 9.99% of the Common Shares of the Company then
issued and  outstanding,  which  prohibition  cannot be  modified  by the holder
before the 61st day after such holder's notice to the Company of its election to
modify such prohibition.

As of March 30, 2009,  Goodnow held  3,529,951  Common  Shares of the Company in
addition to the Common Shares of the Company held by Goodnow  referenced  above.
As of March 30,  2009,  Opportunity  Partners  had the  right to vote  1,000,000
Common  Shares of the  Company  pursuant  to a voting  trust  agreement  between
Opportunity  Partners and the holders of record of those shares. As of March 30,
2009,  Mr.  Cavalier  held  options to  purchase  109,875  Common  Shares of the
Company.

Based upon  information  set forth in the Securities  Purchase  Agreement by and
between the Company and the investors  listed on the Schedule of Buyers attached
thereto, included as Exhibit 10.1 to the Current Report on Form 8-K, dated March
30, 2009,  filed by the Company with the Securities  and Exchange  Commission on
March 31, 2009,  there were  37,467,855  Common Shares of the Company issued and
outstanding as of March 30, 2009. As a result of the foregoing,  for purposes of
Reg.  Section  240.13d-3,  Opportunity  Partners is deemed to  beneficially  own
22,996,154  Common  Shares of the Company,  or 58.1% of the Common Shares of the
Company deemed issued and outstanding as of March 30, 2009.


Item 3.   Source and Amount of Funds or Other Consideration.
          -------------------------------------------------

          This  Item 3 is hereby  amended  by adding  the  following  at the end
thereof:

          All funds used to purchase the  securities  of the Company held by the
Funds  described in this Schedule  13D, as amended,  have come directly from the
assets of the Funds. See Item 5, as amended, for further information.


Item 5.   Interest in Securities of the Issuer.
          ------------------------------------

          This Item 5 is hereby  amended and restated to read in its entirety as
follows:

          Based upon information set forth in the Securities  Purchase Agreement
(the "SPA") by and between the Company and the investors  listed on the Schedule
of Buyers  attached  thereto,  included as Exhibit 10.1 to the Current Report on
Form 8-K,  dated March 30, 2009,  filed by the Company with the  Securities  and
Exchange  Commission on March 31, 2009,  there were 37,467,855  Common Shares of
the Company issued and outstanding as of March 30, 2009.

          As of March 30, 2009,  Opportunity LP held (i) 5,041,469 Common Shares
of the Company,  which includes  1,276,435 Common Shares of the Company owned by
Goodnow, (ii) warrants to purchase up to 660,000 Common Shares of the Company at
an exercise  price of $0.28 per share subject to certain  adjustments,  (iii) 7%
senior convertible notes  (collectively,  "Note 1"), in the aggregate  principal
amount of $300,000,  which are  convertible  into 857,141  Common  Shares of the
Company at a conversion price of $0.35 per share subject to certain adjustments,
(iv)  warrants  ("Warrant  1") to  purchase up to 600,000  Common  Shares of the
Company at an exercise price of $0.50 per share subject to certain  adjustments,
and (v) warrants  ("Warrant 2") to purchase up to 4,687,500 Common Shares of the
Company at an exercise price of $0.35 per share subject to certain  adjustments.
As of March 30, 2009,  Opportunity Ltd held (a) 10,251,003  Common Shares of the
Company, which includes 3,300,653 Common Shares of the Company owned by Goodnow,
(b)  warrants  to  purchase  up to 990,000  Common  Shares of the  Company at an
exercise price of $0.28 per share subject to certain adjustments,  (c) 7% senior
convertible  notes  (together  with  Note  1,  the  "Notes"),  in the  aggregate
principal amount of $700,000, which are convertible into 1,999,998 Common Shares
of the  Company  at a  conversion  price of $0.35 per share  subject  to certain
adjustments,  (d)  warrants  ("Warrant  3") to purchase up to  1,400,000  Common
Shares of the Company at an exercise price of $0.50 per share subject to certain
adjustments, and (e) warrants ("Warrant 4", and together with Warrant 1, Warrant
2 and Warrant 3, the  "Warrants")  to purchase up to 8,705,357  Common Shares of
the  Company  at an  exercise  price of  $0.35  per  share  subject  to  certain
adjustments.  As of March 30, 2009, JV Partners held (1) 1,023,731 Common Shares
of the Company and (2) warrants to purchase up to 500,000  Common  Shares of the
Company at an exercise price of $0.28 per share subject to certain adjustments.




          On March 30, 2009, the Company  entered into the SPA with  Opportunity
LP and  Opportunity  Ltd,  pursuant  to which  the  Company  sold and  issued to
Opportunity  LP  and  Opportunity  Ltd,  for  an  aggregate  purchase  price  of
$1,500,000:  (i)  5,357,143  Common Shares of the Company and (ii) Warrant 2 and
Warrant 4, respectively,  which entitle the holders of such warrants to purchase
in the aggregate 13,392,857 Common Shares of the Company at an exercise price of
$0.35 per share subject to certain adjustments.

          All of the Notes  and the  Warrants  contain  an  issuance  limitation
prohibiting the holder from converting or exercising,  as the case may be, those
securities  to the  extent  that  after  giving  effect  to such  conversion  or
exercise, the holder would beneficially own more than 9.99% of the Common Shares
of the Company then issued and outstanding, which prohibition cannot be modified
by the holder before the 61st day after such  holder's  notice to the Company of
its election to modify such prohibition.

          As of March 30, 2009,  Goodnow  held  3,529,951  Common  Shares of the
Company  in  addition  to the  Common  Shares  of the  Company  held by  Goodnow
referenced  above. As of March 30, 2009,  Opportunity  Partners had the right to
vote 1,000,000 Common Shares of the Company pursuant to a voting trust agreement
between  Opportunity  Partners and the holders of record of those shares.  As of
March 30, 2009, Mr.  Cavalier held options to purchase  109,875 Common Shares of
the Company.

          Opportunity  Partners is the sole member of the investment  manager of
Opportunity LP and  Opportunity  Ltd and, as such,  possesses sole power to vote
and direct the  disposition of all securities of the Company held by Opportunity
LP and Opportunity  Ltd.  Opportunity  Partners is the investment  manager of JV
Partners and, as such,  possesses sole power to vote and direct the  disposition
of all securities of the Company held by JV Partners. Mitchell D. Kaye and David
C.  Cavalier,  the  Co-Managing  Members of Xmark  Capital  Partners,  LLC,  the
Managing Member of Opportunity Partners,  share voting and investment power with
respect  to  all  securities   beneficially   owned  by  Opportunity   Partners.
Opportunity LP and Opportunity Ltd, together,  hold a majority of the membership
interests in Goodnow and, as such,  Opportunity Partners possesses sole power to
vote and  direct  the  disposition  of all  securities  of the  Company  held by
Goodnow.

          As a result of the foregoing,  for purposes of Reg. Section 240.13d-3,
Opportunity  Partners is deemed to beneficially own 22,996,154  Common Shares of
the  Company,  or 58.1% of the Common  Shares of the Company  deemed  issued and
outstanding as of March 30, 2009.

          Except for the transaction described above, there were no transactions
in  Common  Shares,  or  securities   convertible   into,   exercisable  for  or
exchangeable  for Common  Shares by the persons  referenced in Item 2, since the
transactions  set forth and  described  in  Opportunity  Partners'  most  recent
Schedule 13D, having a Date of Event of February 24, 2009.


Item 6.   Contracts, Arrangements, Understandings or Relationships With
          Respect to Securities of the Issuer.
          -----------------------------------

          Item 6 is hereby amended by adding the following at the end thereof:

          On March 30, 2009, the Company  entered into the SPA with  Opportunity
LP and  Opportunity  Ltd,  pursuant  to which  the  Company  sold and  issued to
Opportunity  LP  and  Opportunity  Ltd,  for  an  aggregate  purchase  price  of
$1,500,000:  (i)  5,357,143  Common Shares of the Company and (ii) Warrant 2 and
Warrant 4, respectively,  which entitle the holders of such warrants to purchase
in the aggregate 13,392,857 Common Shares of the Company at an exercise price of
$0.35 per share subject to certain  adjustments.  The  description of the SPA in
this Item 6 is subject to, and  qualified  in its  entirety by, the full text of
the SPA, a copy of which is  incorporated  by  reference  to this  Schedule  13D
Amendment No. 16 as an exhibit pursuant to Item 7 hereof.


Item 7.   Material to be Filed as Exhibits.
          --------------------------------

          Item 7 is hereby amended by adding the following at the end thereof:

          1. Securities Purchase  Agreement,  dated as of March 30, 2009, by and
among  the  Company,  Opportunity  LP  and  Opportunity  Ltd.,  incorporated  by
reference  to Exhibit  10.1 to the Current  Report on Form 8-K,  dated March 30,
2009, filed by the Company with the Securities and Exchange  Commission on March
31, 2009.








                                   Signature
                                   ---------

          After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.


April 29, 2009                        XMARK OPPORTUNITY PARTNERS, LLC
                                      By:  XMARK CAPITAL PARTNERS, LLC
                                           its Managing Member

                                      By:  /s/ Mitchell D. Kaye
                                           -------------------------------------
                                          Name:  Mitchell D. Kaye
                                          Title: Co-Managing Member



  Attention: Intentional misstatements or omissions of fact constitute Federal
                   criminal violations (See 18 U.S.C. 1001).





                                                                       EXHIBIT 1
                                                                       ---------


                         SECURITIES PURCHASE AGREEMENT


          SECURITIES  PURCHASE AGREEMENT (this  "Agreement"),  dated as of March
30, 2009, by and among Aeolus Pharmaceuticals, Inc., a Delaware corporation with
its  headquarters  located at 26361 Crown  Valley  Parkway,  Suite 150,  Mission
Viejo,  California  92691  (the  "Company"),  and the  investors  listed  on the
Schedule of Buyers attached hereto  (individually,  a "Buyer" and  collectively,
the "Buyers").

          WHEREAS:

          A.  The  Company  and each  Buyer is  executing  and  delivering  this
Agreement in reliance upon the exemption from securities  registration  afforded
by Section 4(2) of the Securities Act of 1933, as amended (the "1933 Act"),  and
Rule 506 of Regulation D  ("Regulation  D") as  promulgated by the United States
Securities and Exchange Commission (the "SEC") under the 1933 Act.

          B. Each Buyer, severally and not jointly,  wishes to purchase, and the
Company wishes to sell, upon the terms and conditions  stated in this Agreement,
(i) that aggregate number of shares  (collectively,  the "Shares") of the Common
Stock,  par value $0.01 per share, of the Company (the "Common Stock") set forth
opposite  such  Buyer's  name in column (3) on the  Schedule of Buyers  attached
hereto (the "Schedule of Buyers") and (ii) warrants,  in substantially  the form
attached hereto as Exhibit A (the  "Warrants"),  to acquire up to that number of
additional shares of Common Stock set forth opposite such Buyer's name in column
(4) of the  Schedule  of Buyers  attached  hereto  (collectively,  the  "Warrant
Shares").

          C.   Contemporaneously   with  the  execution  and  delivery  of  this
Agreement, the parties hereto are executing and delivering a Registration Rights
Agreement,  substantially  in the form  attached  hereto as Exhibit B (as may be
amended or restated from time to time,  the  "Registration  Rights  Agreement"),
pursuant to which the Company has agreed to provide certain  registration rights
with  respect to the Shares and the  Warrant  Shares  under the 1933 Act and the
rules and regulations  promulgated  thereunder,  and applicable state securities
laws.

          D. The Shares,  the Warrants and the Warrant Shares  collectively  are
referred to herein as the "Securities."

          NOW, THEREFORE, the Company and each Buyer hereby agree as follows:

          1. PURCHASE AND SALE OF SHARES AND WARRANTS.

                    (a) Purchase and Sale of Shares and Warrants.

                              (i)   Shares   and   Warrants.   Subject   to  the
                    satisfaction  (or  waiver)  of the  conditions  set forth in
                    Sections 6 and 7(i) below,  the Company shall issue and sell
                    to each Buyer,  and each Buyer  severally,  but not jointly,
                    shall  purchase  from the Company,  (x) the number of Shares
                    set forth  opposite  such  Buyer's name in column (3) on the
                    Schedule  of Buyers and (y)  Warrants  to acquire up to that
                    number of Warrant  Shares set forth  opposite  such  Buyer's
                    name in column (4) on the Schedule of Buyers.

                              (ii) Closing. The closing of the purchase and sale
                    of the Shares and Warrants  (the  "Closing")  shall occur at
                    10:00 a.m.,  New York City time, on the date hereof (or such
                    later date as is mutually  agreed to by the Company and each
                    Buyer) after notification of satisfaction (or waiver) of the
                    conditions  to the  Closing set forth in Sections 6 and 7(i)
                    below at the offices of  Lowenstein  Sandler PC, 1251 Avenue
                    of the Americas,  18th Floor,  New York, New York 10020. The
                    date on which the  Closing  occurs is  referred to herein as
                    the "Closing Date."

                              (iii)  Purchase  Price.  The purchase  price to be
                    paid by each  Buyer for the Shares  and the  Warrants  to be
                    purchased  by such Buyer at the Closing  shall be the amount
                    set forth  opposite  such  Buyer's name in column (5) of the
                    Schedule of Buyers (the "Purchase Price").

                    (b) Form of Payment.  On Closing Date,  (i) each Buyer shall
          pay its  respective  Purchase Price to the Company by wire transfer of
          immediately  available funds in accordance with the Company's  written
          wire instructions and (ii) the Company shall deliver to each Buyer (A)
          one or more stock certificates,  evidencing the number of Shares being
          purchased  by such Buyer as set forth  opposite  such  Buyer's name in
          column (3) of the  Schedule  of Buyers,  and (B) one or more  Warrants
          exercisable  for the number of Warrant  Shares set forth opposite such
          Buyer's name in column (4) of the Schedule of Buyers in all cases duly
          executed on behalf of the Company and  registered  in the name of such
          Buyer, or such Buyer's nominee.

          2. BUYER'S  REPRESENTATIONS AND WARRANTIES.  Each Buyer, severally and
not jointly, represents and warrants to the Company that:

                    (a) No Sale or  Distribution.  Such Buyer is  acquiring  the
          Shares  and the  Warrants,  and upon  exercise  of the  Warrants  will
          acquire the Warrant Shares issuable upon exercise of the Warrants, for
          its own account,  not as nominee or agent, and not with a view towards
          distribution  thereof,  and such  Buyer has no  present  intention  of
          selling,  granting any participation in, or otherwise distributing the
          same in  violation  of the  1933  Act or any  state  securities  laws;
          provided,  however,  that by making the  representations  herein, such
          Buyer does not agree to hold any of the  Securities for any minimum or
          other  specific  term  and  reserves  the  right  to  dispose  of  the
          Securities  at  any  time  in   accordance   with  or  pursuant  to  a
          registration statement or an exemption under the 1933 Act and pursuant
          to the applicable  terms of the  Transaction  Documents (as defined in
          Section 3(b)). Such Buyer is acquiring the Securities hereunder in the
          ordinary  course of its business.  Such Buyer does not presently  have
          any  agreement  or  understanding,  directly or  indirectly,  with any
          Person (as  defined in Section  3(r) below) to  distribute  any of the
          Securities.

                    (b) Accredited Investor Status. Such Buyer is an "accredited
          investor"  as that term is defined  in Rule  501(a) of  Regulation  D.

                    (c) Reliance on Exemptions.  Such Buyer understands that the
          Securities  are being  offered  and sold to it in reliance on specific
          exemptions from the registration requirements of United States federal
          and state securities laws and that the Company is relying in part upon
          the truth and  accuracy  of, and such  Buyer's  compliance  with,  the
          representations,    warranties,   agreements,    acknowledgments   and
          understandings  of such Buyer set forth  herein in order to  determine
          the  availability of such exemptions and the eligibility of such Buyer
          to acquire the Securities.

                    (d)  Information.  Such  Buyer has been  furnished  with all
          materials  relating to the  business,  finances and  operations of the
          Company and materials relating to the offer and sale of the Securities
          that have been  requested by such Buyer.  Such Buyer and its advisors,
          if any,  have been  afforded the  opportunity  to ask questions of and
          receive answers from the Company  regarding the Company,  its business
          and the terms and conditions of the offering of the  Securities.  Such
          Buyer  acknowledges  that it has had access to the SEC  Documents  (as
          defined in Section 3(j) below) via the SEC's Electronic Data Gathering
          and Retrieval System or any successor database ("EDGAR"). Neither such
          inquiries nor any other due diligence investigations conducted by such
          Buyer or its advisors,  if any, or its  representatives  shall modify,
          amend  or  affect  such  Buyer's   right  to  rely  on  the  Company's
          representations   and   warranties   contained   herein.   Such  Buyer
          understands and acknowledges that (i) its investment in the Securities
          involves a high  degree of risk,  (ii) it is able to afford a complete
          loss of such  investment  in the  Securities,  and  (iii)  it has such
          knowledge and experience in financial and business  matters that it is
          capable  of  evaluating   the  merits  and  risks  of  the  investment
          contemplated hereby. Such Buyer has sought such accounting,  legal and
          tax  advice  as it  has  considered  necessary  to  make  an  informed
          investment decision with respect to its acquisition of the Securities.

                    (e) No Governmental  Review.  Such Buyer understands that no
          United  States  federal  or state  agency or any other  government  or
          governmental  agency  has  passed  on or made  any  recommendation  or
          endorsement  of the  Securities or the fairness or  suitability of the
          investment in the Securities nor have such authorities  passed upon or
          endorsed the merits of the offering of the Securities.

                    (f) Transfer or Resale.  Such Buyer  understands that except
          as provided in the Registration  Rights Agreement:  (i) the Securities
          have not been and are not being  registered  under the 1933 Act or any
          state securities laws, and may not be offered for sale, sold, assigned
          or transferred unless (A) subsequently registered thereunder, (B) such
          Buyer shall have delivered to the Company an opinion of counsel,  in a
          form  reasonably  acceptable  to the Company,  to the effect that such
          Securities to be sold,  assigned or transferred may be sold,  assigned
          or transferred pursuant to an exemption from such registration, or (C)
          such Buyer  provides the Company with  reasonable  assurance that such
          Securities can be sold,  assigned or transferred  pursuant to Rule 144
          or Rule  144A  promulgated  under  the  1933  Act,  as  amended  (or a
          successor rule thereto)  (collectively,  "Rule 144"); (ii) any sale of
          the  Securities  made  in  reliance  on Rule  144 may be made  only in
          accordance with the terms of Rule 144 and further,  if Rule 144 is not
          applicable,  any resale of the Securities under circumstances in which
          the seller (or the Person through whom the sale is made) may be deemed
          to be an  underwriter  (as that term is  defined  in the 1933 Act) may
          require compliance with some other exemption under the 1933 Act or the
          rules and  regulations  of the SEC  thereunder;  and (iii) neither the
          Company nor any other Person is under any  obligation  to register the
          Securities  under  the 1933  Act or any  state  securities  laws or to
          comply  with the terms and  conditions  of any  exemption  thereunder.
          Notwithstanding  the  foregoing,  the  Securities  may be  pledged  in
          connection  with a bona fide margin account or other loan or financing
          arrangement  secured by the  Securities and such pledge of Securities,
          by itself, shall not be deemed to be a transfer, sale or assignment of
          the  Securities  hereunder,   and  no  Buyer  effecting  a  pledge  of
          Securities  shall be required  to provide the Company  with any notice
          thereof or otherwise make any delivery to the Company pursuant to this
          Agreement  or any other  Transaction  Document  (as defined in Section
          3(b)), including, without limitation, this Section 2(f).

                    (g) Legends. Such Buyer understands that the certificates or
          other instruments  representing the Shares and the Warrants and, until
          such time as the resale of the  Warrant  Shares  have been  registered
          under  the  1933  Act  as  contemplated  by  the  Registration  Rights
          Agreement  or  eligible  to be sold  under  Rule  144 of the  1933 Act
          without regard to the availability of current  financial  information,
          the stock certificates  representing the Warrant Shares, except as set
          forth below,  shall bear any legend as required by the "blue sky" laws
          of any state and a restrictive  legend in substantially  the following
          form (and a stop-transfer order may be placed against transfer of such
          stock certificates):

                    [NEITHER THE ISSUANCE AND SALE OF THE SECURITIES REPRESENTED
                    BY THIS  CERTIFICATE  NOR THE  SECURITIES  INTO WHICH  THESE
                    SECURITIES  ARE   EXERCISABLE   HAVE  BEEN][THE   SECURITIES
                    REPRESENTED BY THIS  CERTIFICATE  HAVE NOT BEEN]  REGISTERED
                    UNDER THE SECURITIES ACT OF 1933, AS AMENDED,  OR APPLICABLE
                    STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR
                    SALE,  SOLD,  TRANSFERRED  OR ASSIGNED (I) IN THE ABSENCE OF
                    (A) AN EFFECTIVE  REGISTRATION  STATEMENT FOR THE SECURITIES
                    UNDER THE  SECURITIES  ACT OF 1933,  AS  AMENDED,  OR (B) AN
                    OPINION OF COUNSEL,  IN A FORM REASONABLY  ACCEPTABLE TO THE
                    COMPANY, THAT REGISTRATION IS NOT REQUIRED UNDER SAID ACT OR
                    (II)  UNLESS  SOLD  PURSUANT  TO RULE 144 OR RULE 144A UNDER
                    SAID ACT.  NOTWITHSTANDING THE FOREGOING, THE SECURITIES MAY
                    BE PLEDGED IN CONNECTION  WITH A BONA FIDE MARGIN ACCOUNT OR
                    OTHER  LOAN  OR   FINANCING   ARRANGEMENT   SECURED  BY  THE
                    SECURITIES.

                    The legend set forth  above shall be removed and the Company
          shall  issue a  certificate  without  such legend to the holder of the
          Securities upon which it is stamped,  if, unless otherwise required by
          state  securities  laws, (i) such Securities are registered for resale
          under the 1933 Act,  (ii) in  connection  with a sale,  assignment  or
          other transfer,  such holder provides the Company with an opinion of a
          law firm  reasonably  acceptable to the Company,  in a form reasonably
          acceptable to the Company, to the effect that such sale, assignment or
          transfer of the Securities may be made without  registration under the
          applicable requirements of the 1933 Act, or (iii) such holder provides
          the Company with reasonable assurance that the Securities can be sold,
          assigned  or  transferred  pursuant  to Rule 144 or Rule  144A.  If an
          opinion is required,  the Company shall be obligated to retain counsel
          in order to cause such counsel to deliver the legal  opinion  referred
          to in clause  (I)(B)  of the  legend  set  forth  above and to pay any
          related fees and expenses of said counsel.

                    (h)  Validity;  Enforcement.  The  execution,  delivery  and
          performance  by such Buyer of each of the  Transaction  Documents  (as
          defined  below)  to which  such  Buyer is a party  have  been duly and
          validly authorized, executed and delivered on behalf of such Buyer and
          shall  constitute  the legal,  valid and binding  obligations  of such
          Buyer  enforceable   against  such  Buyer  in  accordance  with  their
          respective terms,  except (i) as may be limited by general  principles
          of equity or to  applicable  bankruptcy,  insolvency,  reorganization,
          moratorium,  liquidation  and  other  similar  laws  relating  to,  or
          affecting generally,  the enforcement of applicable  creditors' rights
          generally,  (ii) as limited by laws relating to specific  performance,
          injunctive relief of other equitable remedies, and (iii) to the extent
          the  indemnification  provisions  contained in this  Agreement  may be
          limited by applicable laws.

                    (i) No Conflicts. The execution, delivery and performance by
          such Buyer of each of the Transaction Documents to which such Buyer is
          a  party  and  the  consummation  by such  Buyer  of the  transactions
          contemplated  hereby and thereby will not (i) result in a violation of
          the  organizational  documents of such Buyer or (ii) conflict with, or
          constitute  a default  (or an event which with notice or lapse of time
          or both would become a default) under, or give to others any rights of
          termination,   amendment,   acceleration  or   cancellation   of,  any
          agreement,  indenture or instrument to which such Buyer is a party, or
          (iii)  result in a  violation  of any law,  rule,  regulation,  order,
          judgment  or decree  (including  federal  and state  securities  laws)
          applicable to such Buyer, except in the case of clauses (ii) and (iii)
          above, for such conflicts,  defaults, rights or violations which would
          not, individually or in the aggregate,  reasonably be expected to have
          a material  adverse effect on the ability of such Buyer to perform its
          obligations hereunder or under any other Transaction Document to which
          such Buyer is a party.

                    (j) Residency. Such Buyer is a resident of that jurisdiction
          specified below its address on the Schedule of Buyers.

                    (k) Certain Trading  Activities.  Other than with respect to
          the transactions  contemplated  herein, since the time that such Buyer
          was first contacted by the Company or any other Person  regarding this
          investment  in the Company  neither the Buyer nor any  "affiliate"  of
          such  Buyer (as  defined  in Rule 144 of the 1933  Act)  which (x) had
          knowledge of the transactions  contemplated  hereby, (y) has or shares
          discretion   relating  to  such  Buyer's  investments  or  trading  or
          information  concerning such Buyer's investments and (z) is subject to
          such Buyer's review or input concerning such  affiliate's  investments
          or  trading  (collectively,  "Trading  Affiliates")  has  directly  or
          indirectly,  nor has any Person acting on behalf of or pursuant to any
          understanding with such Buyer or Trading Affiliate, effected or agreed
          to effect any  transactions  in the  securities  of the Company.  Such
          Buyer hereby  covenants and agrees not to, and shall cause its Trading
          Affiliates not to, engage, directly or indirectly, in any transactions
          in the securities of the Company or involving the Company's securities
          during  the  period  from the date  hereof  until such time as (i) the
          transactions   contemplated  by  this  Agreement  are  first  publicly
          announced as  described in Section 4(h) hereof or (ii) this  Agreement
          is terminated  in full  pursuant to Section 8 hereof.  Notwithstanding
          the foregoing,  for avoidance of doubt, nothing contained herein shall
          constitute a representation or warranty, or preclude any actions, with
          respect to the  identification of the availability of, or securing of,
          available  shares to borrow in order to effect  short sales or similar
          transactions in the future.

                    (l)  Legal  Investment.  Such  Buyer  acknowledges  that the
          Company has not provided any advice as to whether the Securities are a
          suitable  investment  or whether  the  Securities  constitute  a legal
          investment for such Buyer.

                    (m) Compliance with SEC Telephone Interpretation. Such Buyer
          acknowledges  the SEC's  position set forth in Compliance & Disclosure
          Interpretation  239.10  issued by the SEC's  Division  of  Corporation
          Finance on  November  26,  2008,  and such  Buyer will  adhere to such
          position.

                    (n) General  Solicitation.  Such Buyer is not purchasing the
          Shares and the  Warrants  as a result of any  advertisement,  article,
          notice  or  other  communication   regarding  any  of  the  Securities
          published  in any  newspaper,  magazine or similar  media or broadcast
          over television or radio or presented at any seminar.

                    (o)  Organization.  Such Buyer is an entity duly  organized,
          validly   existing  and  in  good  standing  under  the  laws  of  the
          jurisdiction of its organization with the requisite corporate, limited
          liability company or partnership power and authority to enter into and
          to consummate the transactions  contemplated by this Agreement and the
          other applicable  Transaction Documents and otherwise to carry out its
          obligations hereunder and thereunder.

                    (p) Acknowledgement  Regarding  Insolvency.  Notwithstanding
          anything in this Agreement to the contrary, each Buyer understands and
          acknowledges that the Company and its  Subsidiaries,  individually and
          on a  consolidated  basis,  as of the date  hereof,  and after  giving
          effect to the transactions contemplated hereby to occur at the Closing
          may be, or may become,  Insolvent (as defined below).  For purposes of
          this Section 2(p),  "Insolvent"  means, with respect to any Person (as
          defined in Section 3(r)),  (i) the present fair saleable value of such
          Person's  assets is less than the amount required to pay such Person's
          total  Indebtedness (as defined in Section 3(q)),  (ii) such Person is
          unable to pay its debts and liabilities,  subordinated,  contingent or
          otherwise,  as such debts and liabilities become absolute and matured,
          (iii)  such  Person  intends to incur or  believes  that it will incur
          debts that would be beyond its ability to pay as such debts  mature or
          (iv) such Person has unreasonably  small capital with which to conduct
          the business in which it is engaged as such  business is now conducted
          and is proposed to be conducted.

          3.   REPRESENTATIONS  AND  WARRANTIES  OF  THE  COMPANY.  The  Company
represents and warrants to each of the Buyers that, as of the date hereof and at
all times to and including the Closing  Date,  except as otherwise  described in
the SEC Documents filed with the SEC prior to the date hereof:

                    (a)  Organization  and  Qualification.  The  Company and its
          "Subsidiaries"   (which  for   purposes   of  this   Agreement   means
          "Significant  Subsidiary"  as such  term is  defined  in Rule  1-02 of
          Regulation  S-X  of  the  1933  Act;  which  as of the  date  of  this
          Agreement,  is solely comprised of Aeolus  Sciences,  Inc., a Delaware
          corporation  and a  wholly  owned  subsidiary  of  the  Company),  are
          entities  duly  organized  and  validly  existing  and,  to the extent
          legally   applicable,   in  good  standing   under  the  laws  of  the
          jurisdiction  in which they are formed,  and have the requisite  power
          and  authorization  to own  their  properties  and to  carry  on their
          business  as  now  being  conducted.  Each  of  the  Company  and  its
          Subsidiaries  is duly qualified as a foreign entity to do business and
          to the  extent  legally  applicable,  is in  good  standing  in  every
          jurisdiction  in which its  ownership of property or the nature of the
          business conducted by it makes such qualification necessary, except to
          the extent that the failure to be so qualified or be in good  standing
          would not reasonably be expected to have a Material Adverse Effect. As
          used in this Agreement,  "Material  Adverse Effect" means any material
          adverse  effect  on  the  business,  properties,  assets,  operations,
          results of operations, condition (financial or otherwise) or prospects
          of the  Company  and its  Subsidiaries,  taken as a  whole,  or on the
          transactions  contemplated hereby and the other Transaction  Documents
          or by the agreements and  instruments to be entered into in connection
          herewith or  therewith,  or on the authority or ability of the Company
          to perform its obligations under the Transaction Documents (as defined
          below).  Notwithstanding  the  foregoing,  the  entities  in which the
          Company,  directly or  indirectly,  owns any of the  capital  stock or
          holds an equity or similar interest which are not Subsidiaries,  taken
          as whole, do not have income, revenues or assets which are material to
          the Company and its Subsidiaries,  individually,  or taken as a whole.
          Except for the capital stock of Aeolus Sciences,  Inc. or as set forth
          on Schedule  3(a), the Company does not,  directly or indirectly,  own
          any joint venture or similar entity or hold capital  stock,  equity or
          similar interests.

                    (b) Authorization;  Enforcement;  Validity.  The Company has
          the requisite corporate power and authority to enter into, deliver and
          perform  its  obligations  under this  Agreement,  the  Warrants,  the
          Registration   Rights  Agreement,   the  Irrevocable   Transfer  Agent
          Instructions  (as  defined  in  Section  5(b))  and each of the  other
          agreements  entered  into by the Company  and any Buyer in  connection
          with the  transactions  contemplated by this Agreement  (collectively,
          the  "Transaction   Documents"),   and  to  issue  the  Securities  in
          accordance  with the terms hereof and thereof.  Except as set forth on
          Schedule  3(b),  the execution and delivery of this  Agreement and the
          other Transaction Documents by the Company and the consummation by the
          Company  of  the   transactions   contemplated   hereby  and  thereby,
          including,  without  limitation,  the  issuance  of the Shares and the
          Warrants,  and the  reservation  for  issuance and issuance of Warrant
          Shares  issuable  upon  exercise  of  the  Warrants,  have  been  duly
          authorized by the Company's board of directors, and no further filing,
          consent,  or  authorization  is required by the Company,  its board of
          directors  or  its   stockholders.   This   Agreement  and  the  other
          Transaction  Documents of even date  herewith  have been (and,  to the
          extent the Closing  Date is after the date  hereof,  each  Transaction
          Document  to be entered  into as of the  Closing  Date will have been)
          duly executed and delivered by the Company as of the Closing Date, and
          constitute  (or in the case of  Transaction  Documents  entered on the
          Closing Date if such date is after the date hereof, will constitute as
          of the Closing Date) the legal,  valid and binding  obligations of the
          Company,  enforceable  against  the Company in  accordance  with their
          respective terms,  except (i) as may be limited by general  principles
          of  equity  or  applicable  bankruptcy,  insolvency,   reorganization,
          moratorium,  liquidation  or similar  laws  relating  to, or affecting
          generally,  the enforcement of applicable creditors' rights generally,
          (ii) as limited by laws relating to specific  performance,  injunctive
          relief  of other  equitable  remedies,  and  (iii) to the  extent  the
          indemnification   provisions  contained  in  this  Agreement  and  the
          Registration Rights Agreement may be limited by applicable laws.

                    (c) Issuance of  Securities.  The issuance of the Shares and
          the Warrants are duly  authorized  by the Company and upon issuance in
          accordance  with the  terms of this  Agreement  shall be free from all
          taxes,  liens  and  charges  with  respect  to the  issue  thereof.  A
          sufficient  number  of shares of  Common  Stock  shall  have been duly
          authorized  and  reserved  for  issuance  for purposes of enabling the
          Company to issue that number of shares of Common Stock  issuable  upon
          exercise  of the  Warrants.  Upon  exercise  in  accordance  with  the
          Warrants,  the Warrant Shares will be validly  issued,  fully paid and
          nonassessable  and free from all preemptive or similar rights,  taxes,
          liens and charges with respect to the issue thereof,  with the holders
          being  entitled to all rights  accorded  to a holder of Common  Stock.
          Assuming the accuracy of each of the  representations  and  warranties
          set forth in Section 2 of this  Agreement,  the offer and  issuance by
          the Company of the  Securities is exempt from  registration  under the
          1933 Act.

                    (d) No Conflicts.  Except as set forth on Schedule 3(d), the
          execution,  delivery and  performance  of this Agreement and the other
          Transaction  Documents  by the  Company  and the  consummation  by the
          Company  of  the   transactions   contemplated   hereby  and   thereby
          (including,  without  limitation,  the  issuance  of  the  Shares  and
          Warrants  and  reservation  for  issuance  and issuance of the Warrant
          Shares)  will not (i)  result in a  violation  of any  certificate  of
          incorporation,   certificate   of  formation,   any   certificate   of
          designations or other  constituent  documents of the Company or any of
          its  Subsidiaries,  any  capital  stock of the  Company  or any of its
          Subsidiaries  or bylaws of the Company or any of its  Subsidiaries  or
          (ii)  conflict  with,  or constitute a default (or an event which with
          notice or lapse of time or both would become a default) in any respect
          under,  or  give to  others  any  rights  of  termination,  amendment,
          acceleration   or  cancellation   of,  any  agreement,   indenture  or
          instrument to which the Company or any of its Subsidiaries is a party,
          or (iii) result in a violation of any law,  rule,  regulation,  order,
          judgment or decree  (including  foreign,  federal and state securities
          laws and regulations and the rules and regulations of the OTC Bulletin
          Board (the  "Principal  Market"))  applicable to the Company or any of
          its  Subsidiaries  or by which any property or asset of the Company or
          any of its  Subsidiaries  is bound or affected,  except in the case of
          clauses  (ii) and (iii)  above,  to the  extent  that  such  violation
          conflict,  default or right would not reasonably be expected to have a
          Material Adverse Effect.

                    (e) Consents  and  Filings.  Except as set forth on Schedule
          3(e),  neither the Company nor any of its  Subsidiaries is required to
          obtain any consent,  authorization  or order of, or make any filing or
          registration with, any court, governmental agency or any regulatory or
          self-regulatory  agency  or any  other  Person  in order  to  execute,
          deliver or perform any of its obligations under or contemplated by the
          Transaction  Documents  to which  they are a  party,  in each  case in
          accordance with the terms hereof or thereof, other than (i) the filing
          with the SEC of one or more Registration Statements in accordance with
          the requirements of the Registration Rights Agreement, (ii) the filing
          of Form D with the SEC and such  filings  as are  required  to be made
          under applicable state  securities laws, (iii)  application(s)  to the
          Principal Market for the listing of the Securities for trading thereon
          in the time and manner  required  thereby,  and (iv) filings  required
          pursuant  to  Section  4(h) of this  Agreement.  The  Company  and its
          Subsidiaries  are  unaware  of any facts or  circumstances  that might
          prevent  the  Company  from   obtaining   or  effecting   any  of  the
          registration,   application  or  filings  pursuant  to  the  preceding
          sentence.  The Company is not in violation of the listing requirements
          of the  Principal  Market and has no knowledge of any facts that would
          reasonably  lead to delisting or suspension of the Common Stock in the
          foreseeable future.

                    (f) Acknowledgment Regarding Buyer's Purchase of Securities.
          The Company  acknowledges  and agrees that each Buyer is acting solely
          in the  capacity  of an arm's  length  purchaser  with  respect to the
          Transaction  Documents and the  transactions  contemplated  hereby and
          thereby.

                    (g) No General Solicitation. Neither the Company, nor any of
          its Subsidiaries or affiliates,  nor any Person acting on its or their
          behalf,  has  engaged in any form of general  solicitation  or general
          advertising  (within the meaning of Regulation  D) in connection  with
          the offer or sale of the Securities.

                    (h)  No  Integrated  Offering.  None  of  the  Company,  its
          Subsidiaries,  any of their affiliates, and any Person acting on their
          behalf has,  directly or  indirectly,  made any offers or sales of any
          security  or  solicited  any  offers  to  buy  any   security,   under
          circumstances  that would require  registration of the issuance of any
          of the Securities under the 1933 Act, whether through integration with
          prior offerings or otherwise, or cause this offering of the Securities
          to require approval of stockholders of the Company for purposes of any
          applicable   stockholder  approval  provisions,   including,   without
          limitation,  under  the  rules  and  regulations  of any  exchange  or
          automated  quotation  system  on which  any of the  securities  of the
          Company are listed or designated.

                    (i) Application of Takeover  Protections;  Rights Agreement.
          The  Company  and its board of  directors  have  taken  all  necessary
          action,  if any, in order to render  inapplicable  any  control  share
          acquisition,   business   combination,   poison  pill  (including  any
          distribution under a rights agreement) or other similar  anti-takeover
          provision  under the  Certificate  of  Incorporation  (as  defined  in
          Section 3(q)) or the laws of the state of its  incorporation  which is
          or  could  become   applicable  to  any  Buyer  as  a  result  of  the
          transactions  contemplated  by  this  Agreement,   including,  without
          limitation,  the Company's  issuance of the Securities and any Buyer's
          ownership  of the  Securities.  The Company and its board of directors
          have  taken  all  necessary   action,  if  any,  in  order  to  render
          inapplicable  any  stockholder  rights  plan  or  similar  arrangement
          relating to accumulations of beneficial ownership of Common Stock or a
          change in control of the Company.

                    (j) SEC Documents;  Financial Statements. During the two (2)
          years prior to the date  hereof,  the  Company has filed all  reports,
          schedules,  forms, statements and other documents required to be filed
          by it with  the SEC  pursuant  to the  reporting  requirements  of the
          Securities  Exchange Act of 1934,  as amended (the "1934 Act") (all of
          the foregoing  filed during the two (2) years prior to the date hereof
          and all exhibits included therein and financial statements,  notes and
          schedules  thereto and  documents  incorporated  by reference  therein
          being hereinafter referred to as the "SEC Documents"). The Company has
          made  available  to the  Buyers or their  respective  representatives,
          through EDGAR, true, correct and complete copies of the SEC Documents.
          As of their respective  filing dates, and to the Company's  knowledge,
          the  SEC  Documents   complied  in  all  material  respects  with  the
          requirements  of the 1934 Act and the rules and regulations of the SEC
          promulgated  thereunder  applicable to the SEC Documents,  and did not
          contain  any untrue  statement  of a material  fact or omit to state a
          material fact  required to be stated  therein or necessary in order to
          make the statements  therein,  in the light of the circumstances under
          which they were made, not misleading.  As of their  respective  filing
          dates,  the financial  statements  of the Company  included in the SEC
          Documents complied as to form in all material respects with applicable
          accounting requirements and the published rules and regulations of the
          SEC with respect thereto. Such financial statements have been prepared
          in  accordance   with  generally   accepted   accounting   principles,
          consistently  applied,  during the periods involved (except (i) as may
          be  otherwise  indicated  in such  financial  statements  or the notes
          thereto, or (ii) in the case of unaudited interim  statements,  to the
          extent  they may  exclude  footnotes  or may be  condensed  or summary
          statements) and fairly present in all material  respects the financial
          position of the Company as of the dates thereof and the results of its
          operations and cash flows for the periods then ended (subject,  in the
          case of unaudited  statements,  to normal year-end audit adjustments).
          No other  information  provided  by or on  behalf  of any  officer  or
          director  of the Company to the  Buyers,  solely in their  capacity as
          Buyers, which is not included in the SEC Documents, including, without
          limitation,  information referred to in Section 2(d) of this Agreement
          or in any  disclosure  schedules,  contains any untrue  statement of a
          material fact or omits to state any material  fact  necessary in order
          to make the statements therein, in the light of the circumstance under
          which they are or were made not misleading.

                    (k)  Absence  of  Certain  Changes.  Except  as set forth on
          Schedule 3(k),  since  September 30, 2008,  there has been no material
          adverse  change and no material  adverse  development in the business,
          properties, operations, condition (financial or otherwise), results of
          operations  or  prospects  of the Company or its  Subsidiaries.  Since
          September  30,  2008,  the  Company  has not (i)  declared or paid any
          dividends, (ii) sold any assets,  individually or in the aggregate, in
          excess of $100,000 outside of the ordinary course of business or (iii)
          had capital expenditures,  individually or in the aggregate, in excess
          of $500,000. Neither the Company nor any of its Subsidiaries has taken
          any steps to seek  protection  pursuant to any bankruptcy law nor does
          the Company have any knowledge or reason to believe that its creditors
          intend to initiate  involuntary  bankruptcy  proceedings or any actual
          knowledge of any fact that would reasonably lead a creditor to do so.

                    (l) No  Undisclosed  Events,  Liabilities,  Developments  or
          Circumstances.  No event,  liability,  development or circumstance has
          occurred or exists,  or is  contemplated  to occur with respect to the
          Company,  its Subsidiaries or their respective  business,  properties,
          prospects,  operations or financial condition,  that would be required
          to be disclosed by the Company under  applicable  securities laws on a
          registration  statement  on Form S-1 filed with the SEC relating to an
          issuance and sale by the Company of its Common Stock and which has not
          been publicly announced.

                    (m) Conduct of  Business;  Regulatory  Permits.  Neither the
          Company nor any of its  Subsidiaries is in violation of any term of or
          in default under its Certificate of Incorporation,  any certificate of
          designations  of any  outstanding  series  of  preferred  stock of the
          Company  or the  Bylaws or their  organizational  charter  or  bylaws,
          respectively.  Neither the Company nor any of its  Subsidiaries  is in
          violation of any judgment, decree or order or any statute,  ordinance,
          rule or regulation applicable to the Company or its Subsidiaries,  and
          neither  the  Company  nor any of its  Subsidiaries  will  conduct its
          business in  violation  of any of the  foregoing,  except for possible
          violations  which  could  not,   individually  or  in  the  aggregate,
          reasonably  be expected  to have a Material  Adverse  Effect.  Without
          limiting  the  generality  of the  foregoing,  the  Company  is not in
          violation  of any of the rules,  regulations  or  requirements  of the
          Principal  Market and has no knowledge  of any facts or  circumstances
          that would  reasonably  lead to delisting or  suspension of the Common
          Stock by the Principal  Market in the foreseeable  future.  During the
          two (2) years prior to the date hereof,  (i) the Common Stock has been
          designated for quotation on the Principal Market,  (ii) trading in the
          Common Stock has not been suspended by the SEC or the Principal Market
          and (iii) the Company has received no communication,  written or oral,
          from the SEC or the  Principal  Market  regarding  the  suspension  or
          delisting of the Common Stock from the Principal  Market.  The Company
          and its  Subsidiaries  possess all  certificates,  authorizations  and
          permits issued by the appropriate  regulatory authorities necessary to
          conduct  their  respective  businesses,  except  where the  failure to
          possess such  certificates,  authorizations or permits would not have,
          individually  or in the  aggregate,  a Material  Adverse  Effect,  and
          neither the Company nor any such Subsidiary has received any notice of
          proceedings  relating to the  revocation or  modification  of any such
          certificate, authorization or permit.

                    (n) Foreign Corrupt  Practices.  Neither the Company nor any
          of its  Subsidiaries  nor, to the  Company's  knowledge,  any of their
          respective current or former directors, officers, agents, employees or
          other  Persons  acting  on  behalf  of  the  Company  or  any  of  its
          Subsidiaries  has, in the course of its actions  for, or on behalf of,
          the Company or any of its  Subsidiaries  (i) used any corporate  funds
          for any unlawful contribution,  gift,  entertainment or other unlawful
          expenses  relating  to  political  activity;  (ii) made any  direct or
          indirect  unlawful  payment  to any  foreign  or  domestic  government
          official or employee from  corporate  funds;  (iii)  violated or is in
          violation of any provision of the U.S.  Foreign Corrupt  Practices Act
          of 1977, as amended; or (iv) made any unlawful bribe, rebate,  payoff,
          influence  payment,  kickback or other unlawful payment to any foreign
          or domestic government official or employee.

                    (o)  Sarbanes-Oxley  Act.  Except as set  forth on  Schedule
          3(o),  the  Company  is  in  material  compliance  with  any  and  all
          requirements of the  Sarbanes-Oxley Act of 2002 that are effective and
          applicable to the Company as of the date hereof, and any and all rules
          and  regulations  promulgated by the SEC thereunder that are effective
          and applicable to the Company as of the date hereof.

                    (p)  Transactions  with  Affiliates.  Except as discussed on
          Schedule  3(p),  none of the  officers,  directors or employees of the
          Company  or  any of its  Subsidiaries  is  presently  a  party  to any
          transaction  with the Company or any of its  Subsidiaries  (other than
          for ordinary  course  services as employees,  officers or  directors),
          including any contract,  agreement or other arrangement  providing for
          the  furnishing of services to or by,  providing for rental of real or
          personal  property to or from, or otherwise  requiring  payments to or
          from any such  officer,  director or employee or, to the  knowledge of
          the Company or any of its Subsidiaries, any corporation,  partnership,
          trust or other entity in which any such officer, director, or employee
          has a  substantial  interest  or is an officer,  director,  trustee or
          partner.

                    (q)  Equity  Capitalization.  As of  the  date  hereof,  the
          authorized  capital  stock  of the  Company  consists  of  210,000,000
          shares,  comprised of (x) 200,000,000 shares of Common Stock, of which
          as of the date hereof,  32,110,712  shares are issued and outstanding,
          and (y)  10,000,000  shares of  preferred  stock,  par value $0.01 per
          share,  of which 600,000 shares are designated  Series B nonredeemable
          convertible  preferred  stock,  of which 475,087 shares are issued and
          outstanding,  and no other shares of the Company's preferred stock are
          issued or outstanding. All outstanding shares of the Company's capital
          stock have been, or upon issuance will be,  validly issued and are, or
          upon  issuance  will be,  fully  paid  and  nonassessable.  Except  as
          described  on  Schedule  3(q),  with  respect  to any  debt or  equity
          instruments  of the  Company  and its  Subsidiaries,  (i)  none of the
          Company's  capital stock is subject to preemptive  rights or any other
          similar rights or any liens or  encumbrances  suffered or permitted by
          the Company; (ii) there are no outstanding options,  warrants,  scrip,
          rights  to  subscribe  to,  calls  or  commitments  of  any  character
          whatsoever  relating to, or securities or rights  convertible into, or
          exercisable or  exchangeable  for, any capital stock of the Company or
          any of its Subsidiaries, or contracts, commitments,  understandings or
          arrangements by which the Company or any of its Subsidiaries is or may
          become bound to issue  additional  capital stock of the Company or any
          of its Subsidiaries or options,  warrants,  scrip, rights to subscribe
          to, calls or commitments of any character  whatsoever  relating to, or
          securities or rights  convertible into, or exercisable or exchangeable
          for,  any  capital  stock of the  Company or any of its  Subsidiaries;
          (iii) there are no financing  statements  securing  obligations in any
          material  amounts,  either  singly  or  in  the  aggregate,  filed  in
          connection with the Company or any of its Subsidiaries; (iv) there are
          no  agreements or  arrangements  under which the Company or any of its
          Subsidiaries  is  obligated  to  register  the  sale  of any of  their
          securities  under  the  1933  Act  (except  the  Registration   Rights
          Agreement);  (v) there are no outstanding securities or instruments of
          the Company or any of its Subsidiaries which contain any redemption or
          similar   provisions,   and  there  are  no  contracts,   commitments,
          understandings  or  arrangements  by which the  Company  or any of its
          Subsidiaries  is or may  become  bound  to  redeem a  security  of the
          Company or any of its  Subsidiaries;  (vi) there are no  securities or
          instruments  containing  anti-dilution or similar provisions that will
          be triggered by the issuance of the Securities; (vii) the Company does
          not have any stock  appreciation  rights or "phantom  stock"  plans or
          agreements or any similar plan or agreement; and (vii) the Company and
          its  Subsidiaries  have no liabilities  or obligations  required to be
          disclosed  in the  SEC  Documents  but  not so  disclosed  in the  SEC
          Documents,  other than those  incurred in the  ordinary  course of the
          Company's  or  its  Subsidiaries'  respective  businesses  and  which,
          individually or in the aggregate,  do not or would not have a Material
          Adverse Effect. The Company has made available to the Buyers,  through
          EDGAR, true, correct and complete copies of the Company's  certificate
          of incorporation,  as amended and as in effect on the date hereof (the
          "Certificate of Incorporation"),  and the Company's bylaws, as amended
          and as in effect on the date hereof (the "Bylaws").

                    (r) Indebtedness  and Other  Contracts.  Except as set forth
          under the  agreements or other  arrangements  listed on Schedule 3(r),
          neither  the  Company  nor  any  of  its   Subsidiaries  (i)  has  any
          outstanding  Indebtedness  (as defined below),  (ii) is a party to any
          contract,  agreement or instrument, the violation of which, or default
          under which,  by the other  party(ies) to such contract,  agreement or
          instrument  could  reasonably  be  expected  to result  in a  Material
          Adverse  Effect,  (iii) is in  violation  of any term of or in default
          under  any  contract,   agreement  or   instrument   relating  to  any
          Indebtedness,  except where such  violations  and  defaults  would not
          result,  individually  or in  the  aggregate,  in a  Material  Adverse
          Effect,  or (iv) is a party to any  contract,  agreement or instrument
          relating  to  any  Indebtedness,  the  performance  of  which,  in the
          judgment  of the  Company's  officers,  has or is  expected  to have a
          Material  Adverse  Effect.   For  purposes  of  this  Agreement:   (x)
          "Indebtedness"  of any  Person  means,  without  duplication  (A)  all
          indebtedness   for  borrowed  money,   (B)  all  obligations   issued,
          undertaken  or assumed as the deferred  purchase  price of property or
          services,   including   (without   limitation)   "capital  leases"  in
          accordance with generally accepted  accounting  principles (other than
          trade payables  entered into in the ordinary course of business),  (C)
          all  reimbursement  or payment  obligations with respect to letters of
          credit,   surety  bonds  and  other  similar   instruments,   (D)  all
          obligations   evidenced  by  notes,   bonds,   debentures  or  similar
          instruments, including obligations so evidenced incurred in connection
          with the  acquisition  of  property,  assets  or  businesses,  (E) all
          indebtedness  created or arising under any  conditional  sale or other
          title retention  agreement,  or incurred as financing,  in either case
          with respect to any property or assets  acquired  with the proceeds of
          such  indebtedness  (even though the rights and remedies of the seller
          or bank under such  agreement  in the event of default  are limited to
          repossession or sale of such property),  (F) all monetary  obligations
          in excess of $100,000 under any leasing or similar  arrangement which,
          in  connection   with  generally   accepted   accounting   principles,
          consistently applied for the periods covered thereby, is classified as
          a capital  lease,  (G) all  indebtedness  referred  to in clauses  (A)
          through  (F)  above  secured  by (or  for  which  the  holder  of such
          Indebtedness  has an existing  right,  contingent or otherwise,  to be
          secured by) any mortgage,  lien, pledge, charge,  security interest or
          other  encumbrance  upon  or in  any  property  or  assets  (including
          accounts and  contract  rights)  owned by any Person,  even though the
          Person  which owns such assets or  property  has not assumed or become
          liable for the payment of such  indebtedness,  and (H) all  Contingent
          Obligations in respect of indebtedness or obligations of others of the
          kinds  referred to in clauses (A) through (G) above;  (y)  "Contingent
          Obligation" means, as to any Person, any direct or indirect liability,
          contingent  or   otherwise,   of  that  Person  with  respect  to  any
          indebtedness, lease, dividend or other obligation of another Person if
          the primary purpose or intent of the Person  incurring such liability,
          or the primary effect thereof,  is to provide assurance to the obligee
          of such liability  that such liability will be paid or discharged,  or
          that any  agreements  relating  thereto will be complied with, or that
          the holders of such  liability will be protected (in whole or in part)
          against  loss  with  respect  thereto;   and  (z)  "Person"  means  an
          individual,  a  limited  liability  company,  a  partnership,  a joint
          venture, a corporation, a trust, an unincorporated  organization and a
          government or any department or agency thereof.

                    (s)  Absence  of  Litigation.  There  is  no  action,  suit,
          proceeding,  inquiry  or  investigation  before  or by  the  Principal
          Market, any court,  public board,  government agency,  self-regulatory
          organization  or body  pending or, to the  knowledge  of the  Company,
          threatened   against  or   affecting   the   Company  or  any  of  its
          Subsidiaries, the Common Stock or any of the Company's Subsidiaries or
          any of the Company's or its Subsidiaries' officers or directors.

                    (t) Insurance.  The Company and each of its Subsidiaries are
          insured by insurers of  recognized  financial  responsibility  against
          such losses and risks and in such amounts as management of the Company
          believes to be prudent and  customary in the  businesses  in which the
          Company  and its  Subsidiaries  are  engaged.  Except  as set forth on
          Schedule  3(t),  neither the Company nor any such  Subsidiary  has any
          reason  to  believe  that it will  not be able to renew  its  existing
          insurance  coverage  as and when such  coverage  expires  or to obtain
          similar coverage from similar insurers as may be necessary to continue
          its business at a cost that would not have a Material Adverse Effect.

                    (u) Employee Relations.

                              (i)   Neither   the   Company   nor   any  of  its
                    Subsidiaries  is  a  party  to  any  collective   bargaining
                    agreement or employs any member of a union.  The Company and
                    its  Subsidiaries  believe that their  relations  with their
                    employees are good.  No executive  officer of the Company or
                    any of its Subsidiaries has notified the Company or any such
                    Subsidiary that such officer intends to leave the Company or
                    any such  Subsidiary or otherwise  terminate  such officer's
                    employment  with  the  Company  or any such  Subsidiary.  No
                    executive officer of the Company or any of its Subsidiaries,
                    is, or is now  expected to be, in  violation of any material
                    term of any employment contract, confidentiality, disclosure
                    or  proprietary   information   agreement,   non-competition
                    agreement,  or  any  other  contract  or  agreement  or  any
                    restrictive  covenant,  and the continued employment of each
                    such  executive  officer does not subject the Company or any
                    of its  Subsidiaries to any liability with respect to any of
                    the foregoing matters.

                              (ii)  Except as set forth on  Schedule  3(o),  the
                    Company and its  Subsidiaries,  to their  knowledge,  are in
                    compliance with all federal,  state,  local and foreign laws
                    and regulations respecting labor,  employment and employment
                    practices and benefits,  terms and  conditions of employment
                    and  wages  and  hours,   except  where  failure  to  be  in
                    compliance   would  not,  either   individually  or  in  the
                    aggregate,  reasonably  be  expected to result in a Material
                    Adverse Effect.

                    (v) Title. Except as set forth on Schedule 3(v), the Company
          and its  Subsidiaries  have good and marketable title in fee simple to
          all  real  property  and  good and  marketable  title to all  personal
          property  owned  by them  which is  material  to the  business  of the
          Company  and its  Subsidiaries,  in each  case  free and  clear of all
          liens,  encumbrances  and defects or such as do not materially  affect
          the value of such property and do not  materially  interfere  with the
          use made and  proposed to be made of such  property by the Company and
          any of its  Subsidiaries.  Any real property and facilities held under
          lease  by the  Company  and any of its  Subsidiaries  are held by them
          under valid, subsisting and enforceable leases with such exceptions as
          are not material and do not  interfere  with the use made and proposed
          to be made of such  property  and  buildings  by the  Company  and its
          Subsidiaries,   except  (i)  as  limited  by  applicable   bankruptcy,
          insolvency,  fraudulent  transfer,   reorganization,   moratorium  and
          similar  laws  of  general  applicability,  relating  to or  affecting
          creditors'  rights  generally,  (ii) as  limited by laws  relating  to
          specific  performance,  injunctive relief or other equitable remedies,
          and (iii) to the extent any  indemnification  provisions  contained in
          such leases may be limited by applicable laws.

                    (w)  Intellectual  Property  Rights.  The  Company  and  its
          Subsidiaries  own or possess  adequate  rights or  licenses to use all
          trademarks,  service  marks  and all  applications  and  registrations
          therefor,  trade names, patents, patent rights,  copyrights,  original
          works of authorship,  inventions, trade secrets and other intellectual
          property rights ("Intellectual  Property Rights") necessary to conduct
          their  respective   businesses  as  conducted  on  the  date  of  this
          Agreement. Except as set forth on Schedule 3(w), none of the Company's
          registered,  or applied for, Intellectual Property Rights have expired
          or  terminated  or have been  abandoned,  or are expected to expire or
          terminate  or expected to be  abandoned,  within  three years from the
          date of this Agreement,  in each case except as have not had and could
          not reasonably be expected to have a Material  Adverse Effect.  To the
          knowledge of the Company,  no product or service of the Company or its
          Subsidiaries  infringes the  Intellectual  Property  Rights of others.
          There is no claim,  action or proceeding being made or brought,  or to
          the knowledge of the Company or its  Subsidiaries,  being  threatened,
          against the Company or its Subsidiaries regarding (i) its Intellectual
          Property Rights,  or (ii) that the products or services of the Company
          or its  Subsidiaries  infringe  the  Intellectual  Property  Rights of
          others.  Neither the Company nor any of its  Subsidiaries  is aware of
          any  facts  or  circumstances  which  might  give  rise  to any of the
          foregoing infringements or claims, actions or proceedings. The Company
          and its  Subsidiaries  have  taken  reasonable  security  measures  to
          protect  the  secrecy,  confidentiality  and  value  of all  of  their
          Intellectual Property Rights, except where failure to do so could not,
          individually  or in the  aggregate,  reasonably  be expected to have a
          Material Adverse Effect.

                    (x) Environmental Laws. The Company and its Subsidiaries, to
          their knowledge,  (i) are in compliance with any and all Environmental
          Laws  (as  hereinafter  defined),  (ii)  have  received  all  permits,
          licenses  or  other  approvals   required  of  them  under  applicable
          Environmental  Laws to conduct their  respective  businesses and (iii)
          are in  compliance  with all terms and  conditions of any such permit,
          license or approval where, in each of the foregoing  clauses (i), (ii)
          and (iii),  the failure to so comply could be  reasonably  expected to
          have, individually or in the aggregate, a Material Adverse Effect. The
          term "Environmental  Laws" means all federal,  state, local or foreign
          laws  relating  to  pollution  or  protection  of human  health or the
          environment  (including,  without  limitation,  ambient  air,  surface
          water,  groundwater,  land surface or subsurface  strata),  including,
          without limitation, laws relating to emissions,  discharges,  releases
          or threatened  releases of  chemicals,  pollutants,  contaminants,  or
          toxic or  hazardous  substances  or wastes  (collectively,  "Hazardous
          Materials")  into  the  environment,  or  otherwise  relating  to  the
          manufacture,   processing,   distribution,  use,  treatment,  storage,
          disposal, transport or handling of Hazardous Materials, as well as all
          authorizations,   codes,   decrees,   demands   or   demand   letters,
          injunctions,  judgments,  licenses, notices or notice letters, orders,
          permits, plans or regulations issued, entered, promulgated or approved
          thereunder.

                    (y) Tax Status. The Company and each of its Subsidiaries (i)
          has made or filed all foreign,  federal and state income and all other
          tax returns,  reports and declarations required by any jurisdiction to
          which it is  subject,  (ii) has paid all taxes and other  governmental
          assessments  and  charges  that  are  material  in  amount,  shown  or
          determined to be due on such returns, reports and declarations, except
          those  being  contested  in good  faith and (iii) has set aside on its
          books provisions  reasonably adequate for the payment of all taxes for
          periods  subsequent to the periods to which such  returns,  reports or
          declarations  apply.  There are no unpaid taxes in any material amount
          claimed to be due by the taxing authority of any jurisdiction, and the
          officers of the Company know of no basis for any such claim.

                    (z) Internal Accounting and Disclosure Controls. The Company
          and each of its Subsidiaries  maintain a system of internal accounting
          controls   sufficient  to  provide   reasonable   assurance  that  (i)
          transactions are executed in accordance with  management's  general or
          specific  authorizations,  (ii) transactions are recorded as necessary
          to permit  preparation  of financial  statements  in  conformity  with
          generally  accepted  accounting  principles  and to maintain asset and
          liability  accountability,  (iii)  access to assets or  incurrence  of
          liabilities is permitted only in accordance with management's  general
          or specific  authorization  and (iv) the recorded  accountability  for
          assets  and  liabilities  is  compared  with the  existing  assets and
          liabilities at reasonable  intervals and  appropriate  action is taken
          with respect to any difference.  Except as set forth on Schedule 3(z),
          the Company maintains disclosure controls and procedures (as such term
          is defined in Rule 13a-14  under the 1934 Act) that are  effective  in
          ensuring that  information  required to be disclosed by the Company in
          the reports  that it files or submits  under the 1934 Act is recorded,
          processed,  summarized and reported, within the time periods specified
          in the  rules  and forms of the SEC,  including,  without  limitation,
          controls  and  procedures  designed  in  to  ensure  that  information
          required to be  disclosed  by the Company in the reports that it files
          or submits under the 1934 Act is accumulated  and  communicated to the
          Company's  management,  including its principal  executive  officer or
          officers  and  its  principal   financial  officer  or  officers,   as
          appropriate,  to allow timely decisions regarding required disclosure.
          Except as set forth on Schedule  3(z),  during the twelve months prior
          to the date hereof  neither  the  Company nor any of its  Subsidiaries
          have  received  any  notice  or  correspondence  from  any  accountant
          relating  to any  material  weakness  in any  part  of the  system  of
          internal   accounting   controls   of  the   Company  or  any  of  its
          Subsidiaries.

                    (aa)   Off   Balance   Sheet   Arrangements.   There  is  no
          transaction, arrangement, or other relationship between the Company or
          any of its  Subsidiaries  and an  unconsolidated  or other off balance
          sheet  entity that is required to be  disclosed  by the Company in its
          1934 Act filings and is not so  disclosed or that  otherwise  would be
          reasonably likely to have a Material Adverse Effect.

                    (bb) Investment Company Status.  Neither the Company nor any
          of its  Subsidiaries  is,  and  upon  consummation  of the sale of the
          Securities neither the Company nor any of its Subsidiaries will be, an
          "investment  company," a company controlled by an "investment company"
          or an "affiliated person" of, or "promoter" or "principal underwriter"
          for,  an  "investment  company"  as  such  terms  are  defined  in the
          Investment Company Act of 1940, as amended.

                    (cc)  Transfer   Taxes.  On  the  Closing  Date,  all  stock
          transfer, documentary stamp taxes or other taxes (other than income or
          similar  taxes) which are required to be paid in  connection  with the
          sale and transfer of the Securities to be sold to each Buyer hereunder
          on the Closing Date will be, or will have been, fully paid or provided
          for by the Company,  and all laws  imposing such taxes will be or will
          have been complied with.

                    (dd)  Manipulation of Price. The Company has not, and to its
          knowledge  no one acting on its behalf  has,  (i) taken,  directly  or
          indirectly,  any  action  designed  to  cause  or  to  result  in  the
          stabilization  or  manipulation  of the price of any  security  of the
          Company  to  facilitate  the sale or resale of any of the  Securities,
          (ii) sold, bid for, purchased, or paid any compensation for soliciting
          purchases of, any of the Securities, or (iii) paid or agreed to pay to
          any person any  compensation  for  soliciting  another to purchase any
          other securities of the Company.

                    (ee)  Disclosure.  The Company  confirms that neither it nor
          any other  Person  acting on its behalf has provided any of the Buyers
          or their agents or counsel,  solely in their  capacity as  prospective
          Buyers,  with any information  that constitutes or could reasonably be
          expected to constitute material,  nonpublic  information.  The Company
          understands  and  confirms  that each of the  Buyers  will rely on the
          foregoing  representations in effecting  transactions in securities of
          the  Company.  All  disclosure  provided to the Buyers  regarding  the
          Company  or  any  of  its   Subsidiaries,   their   business  and  the
          transactions  contemplated  hereby,  including  the  Schedules to this
          Agreement,  furnished  by or on  behalf  of the  Company  is true  and
          correct and does not contain any untrue  statement of a material  fact
          or omit to state  any  material  fact  necessary  in order to make the
          statements made therein, in the light of the circumstances under which
          they were  made,  not  misleading.  Each press  release  issued by the
          Company  or any of its  Subsidiaries  during the  twelve  (12)  months
          preceding  the date of this  Agreement  did not at the time of release
          contain  any untrue  statement  of a material  fact or omit to state a
          material fact  required to be stated  therein or necessary in order to
          make the statements  therein,  in the light of the circumstances under
          which they were made, not  misleading.  No event or  circumstance  has
          occurred or  information  exists with respect to the Company or any of
          its  Subsidiaries  or its or their  business,  properties,  prospects,
          operations or financial conditions,  which, under applicable law, rule
          or  regulation,  requires  public  disclosure or  announcement  by the
          Company but which has not been so publicly  announced  or disclosed in
          accordance with such requirements. The Company acknowledges and agrees
          that no Buyer makes or has made any representations or warranties with
          respect  to the  transactions  contemplated  hereby  other  than those
          specifically  set forth in Section 2.  Notwithstanding  the foregoing,
          the Company and each Buyer  acknowledge that Buyer has or may have one
          or more agents  serving as a director on the Board of Directors of the
          Company and that the receipt or awareness of any  information  related
          to the Company gained by any such director in his or her capacity as a
          director  of the  Company  shall  not be  deemed a  violation  of this
          paragraph by the Company.

                    (ff)  Acknowledgement  Regarding  Buyers' Trading  Activity.
          Anything  in  this  Agreement  or  elsewhere  herein  to the  contrary
          notwithstanding,   but  subject  to  compliance  by  the  Buyers  with
          applicable law and the terms of this  Agreement,  it is understood and
          acknowledged  by the  Company  (i) that none of the  Buyers  have been
          asked by the Company or its  Subsidiaries to agree,  nor has any Buyer
          agreed with the Company or its Subsidiaries, to desist from purchasing
          or  selling,  long  and/or  short,   securities  of  the  Company,  or
          "derivative"  securities based on securities  issued by the Company or
          to hold the  Securities  for any  specified  term;  (ii)  that past or
          future  open  market or other  transactions  by any Buyer,  including,
          without limitation,  short sales or "derivative" transactions,  before
          or after the closing of this or future private placement transactions,
          may   negatively   impact   the   market   price   of  the   Company's
          publicly-traded securities;  (iii) that any Buyer, and counter parties
          in  "derivative"  transactions  to which  any  such  Buyer is a party,
          directly or indirectly,  presently may have a "short"  position in the
          Common Stock; and (iv) that each Buyer shall not be deemed to have any
          affiliation with or control over any arm's length counter-party in any
          "derivative"   transaction.   The  Company  further   understands  and
          acknowledges  that (a) one or more Buyers may engage in hedging and/or
          trading  activities  at  various  times  during  the  period  that the
          Securities are outstanding,  including, without limitation, during the
          periods that the value of the Warrant Shares  deliverable with respect
          to Securities are being determined and (b) such hedging and/or trading
          activities   (if  any)  could   reduce  the  value  of  the   existing
          stockholders'  equity  interests  in the Company at and after the time
          that the hedging and/or trading activities are being conducted.

                    (gg)  Placement  Agents.  Except  as set  forth on  Schedule
          3(gg), neither the Company nor any of its subsidiaries has engaged any
          placement agent or other agent in connection with the placement, offer
          or sale of the Securities.

          4. COVENANTS.

                    (a) Best  Efforts.  Each party shall use its best efforts to
          timely  satisfy  each  of  the  conditions  to be  satisfied  by it as
          provided in Sections 6 and 7 of this Agreement.

                    (b) Form D and Blue Sky. The Company agrees to file a Form D
          with respect to the Securities as required  under  Regulation D and to
          provide a copy thereof to each Buyer promptly  after such filing.  The
          Company shall,  on or before the Closing Date, take such action as the
          Company shall reasonably  determine is necessary in order to obtain an
          exemption for or to qualify the  Securities  for sale to the Buyers at
          the Closing pursuant to this Agreement under applicable  securities or
          "Blue Sky" laws of the  states of the  United  States (or to obtain an
          exemption from such qualification),  and shall provide evidence of any
          such  action so taken to the Buyers on or prior to the  Closing  Date.
          The Company  shall make all filings and reports  relating to the offer
          and sale of the  Securities  required under  applicable  securities or
          "Blue  Sky" laws of the  states of the  United  States  following  the
          Closing Date.

                    (c)  Reporting  Status.  Until the date on which the  Buyers
          shall have sold all the  Warrant  Shares and none of the  Warrants  is
          outstanding  (the "Reporting  Period"),  the Company shall timely file
          (or  obtain   extensions  in  respect  thereof  and  file  within  the
          applicable grace period) all reports required to be filed with the SEC
          pursuant to the 1934 Act. As long as any Buyer owns Securities, if the
          Company is not required to file  reports  pursuant to the 1934 Act, it
          will prepare and furnish to the Buyers and make publicly  available in
          accordance  with Rule 144(c) such  information  as is required for the
          Buyers to sell the  Securities  under Rule 144.  The  Company  further
          covenants  that it will take  such  further  action  as any  holder of
          Securities may reasonably request, to the extent required from time to
          time  to  enable   such  Person  to  sell  such   Securities   without
          registration  under the Securities Act within the  requirements of the
          exemption provided by Rule 144, including, without limitation, causing
          the  transfer  agent for the Common  Stock to remove  legends and stop
          transfer  instructions with respect to any Warrant Shares which may be
          sold  under Rule 144  without  regard to the  availability  of current
          financial information.

                    (d) Use of Proceeds.  The Company will use the proceeds from
          the sale of the Securities for general corporate purposes, and not for
          (x) the repayment of any  outstanding  Indebtedness  of the Company or
          any of its  Subsidiaries  at any time prior to the scheduled  maturity
          date thereof or (y) the  redemption or repurchase of any of its or its
          Subsidiaries'  equity  securities  other than the repurchase of equity
          issued to or held by employees, officers, directors and consultants of
          the Company or a Subsidiary  upon  termination of their  employment or
          services with the Company or a Subsidiary.

                    (e) Financial  Information.  The Company  agrees to send the
          following  to each Buyer (or each  transferee  thereof as permitted by
          Section 2(f)) during the Reporting Period (i) unless the following are
          filed  with the SEC  through  EDGAR and are  available  to the  public
          through the EDGAR system, within one (1) Business Day after the filing
          thereof  with the SEC,  a copy of its  Annual  Reports  and  Quarterly
          Reports on Form 10-K,  10-Q, any interim  reports or any  consolidated
          balance sheets,  income  statements,  stockholders'  equity statements
          and/or cash flow  statements  for any period  other than  annual,  any
          Current  Reports on Form 8-K and any  registration  statements  (other
          than on Form S-8) or amendments  filed  pursuant to the 1933 Act, (ii)
          on the same day as the release  thereof,  facsimile or e-mailed copies
          of  all  press   releases   issued  by  the  Company  or  any  of  its
          Subsidiaries,  and (iii)  copies of any notices and other  information
          made available or given to all stockholders of the Company  generally,
          contemporaneously  with the making  available or giving thereof to the
          stockholders.  As used herein, "Business Day" means any day other than
          Saturday, Sunday or other day on which commercial banks in The City of
          New York are authorized or required by law to remain closed.

                    (f) Listing.  The Company shall promptly  secure the listing
          of the Shares and the  Warrant  Shares upon each  national  securities
          exchange and automated quotation system, if any, upon which the Common
          Stock is then  listed  (subject to official  notice of  issuance)  and
          shall maintain such listing of all Shares and Warrant Shares from time
          to time issuable  under the terms of the  Transaction  Documents.  The
          Company shall maintain the Common Stock's  authorization for quotation
          on  the  Principal  Market.   Neither  the  Company  nor  any  of  its
          Subsidiaries shall take any action which would be reasonably  expected
          to result in the  delisting or  suspension  of the Common Stock on the
          Principal  Market.  The  Company  shall pay all fees and  expenses  in
          connection with satisfying its obligations under this Section 4(f).

                    (g) Expenses. Subject to Section 8 below, the parties hereto
          shall pay their own costs and expenses in connection herewith,  except
          that, the Company shall pay the  documented,  reasonable and customary
          third party  expenses  incurred by the Buyers in  connection  with the
          negotiation,  preparation and execution of the Transaction  Documents,
          including  the  reasonable  fees and  expenses  of one  counsel to the
          Buyers,  which shall be Lowenstein  Sandler PC. Such expenses shall be
          paid not later than, in the case of fees and expenses  associated with
          the Closing, five (5) Business Days following the Closing.

                    (h)   Disclosure   of   Transactions   and  Other   Material
          Information. On or before 11:30 a.m., New York City time, on the first
          Business Day following the date of this  Agreement,  the Company shall
          issue a press release and file a Current Report on Form 8-K describing
          the  terms  of  the  transactions   contemplated  by  the  Transaction
          Documents  in the form  required  by the 1934  Act and  attaching  the
          material Transaction  Documents (including,  without limitation,  this
          Agreement,  the form of Warrant and the Registration Rights Agreement)
          as  exhibits  to  such  filing  (such   filing,   including  all  such
          attachments,  the "8-K Filing").  From and after the filing of the 8-K
          Filing with the SEC, no Buyer shall be in  possession of any material,
          nonpublic  information  received  from  the  Company  or  any  of  its
          Subsidiaries or any of their respective officers, directors, employees
          or agents, that is not disclosed in the 8-K Filing; provided, however,
          that the mere  possession  of such  information  by a director  of the
          Company  who is  affiliated  with a Buyer  shall not be required to be
          disclosed in the 8-K Filing; and provided further that Buyer may have,
          or may be deemed to have,  material,  non-public  information received
          from the Company or its officers, directors,  employees or agents as a
          result of Buyer having one or more agents serving as a director on the
          Board of Directors of the  Company.  The Company  shall not, and shall
          cause each of its  Subsidiaries  and its and each of their  respective
          officers, directors,  employees and agents, not to, provide any Buyer,
          solely in Buyer's  capacity as a purchaser  of  Securities  hereunder,
          with any material,  nonpublic information regarding the Company or any
          of its  Subsidiaries  from and after the filing of the 8-K Filing with
          the SEC without the express written consent of such Buyer.  Subject to
          the foregoing,  neither the Company,  its  Subsidiaries  nor any Buyer
          shall issue any press  releases or any other  public  statements  with
          respect to the transactions  contemplated hereby;  provided,  however,
          that the Company shall be entitled,  without the prior approval of any
          Buyer,  to make any press  release  or other  public  disclosure  with
          respect to such  transactions  (i) in substantial  conformity with the
          8-K Filing and contemporaneously  therewith and (ii) as is required by
          applicable  law and  regulations  (provided that in the case of clause
          (i) each Buyer shall be  consulted by the Company in  connection  with
          any  such  press  release  or  other  public  disclosure  prior to its
          release).

                    (i) Reservation of Shares. The Company shall take all action
          necessary  to at all  times  have  authorized,  and  reserved  for the
          purpose of issuance, a sufficient number of shares of Common Stock for
          the purpose of enabling  the Company to issue that number of shares of
          Common Stock  issuable upon exercise of the Warrants  (without  taking
          into account any limitations on the exercise of the Warrants set forth
          in the Warrants).

                    (j)   Fundamental   Transactions.   So  long  as  any  Buyer
          beneficially  owns any  Securities,  the Company shall not be party to
          any Fundamental  Transaction  (as defined in the Warrants)  unless the
          Company is in  compliance  with the  applicable  provisions  governing
          Fundamental Transactions set forth in the Warrants.

                    (k) Conduct of Business. The business of the Company and its
          Subsidiaries shall not be conducted in violation of any law, ordinance
          or regulation of any governmental entity, except where such violations
          would  not  result,  either  individually  or in the  aggregate,  in a
          Material Adverse Effect.

          5. REGISTER; TRANSFER AGENT INSTRUCTIONS.

                    (a) Register.  The Company  shall  maintain at its principal
          executive offices (or such other office or agency of the Company as it
          may designate by notice to each holder of Securities),  a register for
          the Shares and the Warrants in which the Company shall record the name
          and  address of the  Person in whose name the Shares and the  Warrants
          have been issued  (including the name and address of each transferee),
          the number of Shares  held by such  Person,  and the number of Warrant
          Shares issuable upon exercise of the Warrants held by such Person. The
          Company shall keep the register open and available at all times during
          business   hours   for   inspection   of  any   Buyer  or  its   legal
          representatives,   upon  reasonable  advance  written  notice  to  the
          Company.

                    (b) Transfer  Agent  Instructions.  The Company  shall issue
          irrevocable   instructions  to  its  transfer  agent,  American  Stock
          Transfer and Trust Company,  and any  subsequent  transfer  agent,  to
          issue certificates or credit shares to the applicable balance accounts
          at The  Depository  Trust Company  ("DTC"),  registered in the name of
          each  Buyer  or its  respective  nominee(s),  for the  Shares  and the
          Warrant  Shares issued at the Closing or upon exercise of the Warrants
          in such  amounts as  specified  from time to time by each Buyer to the
          Company  upon  exercise  of the  Warrants  in the  form of  Exhibit  C
          attached hereto (the "Irrevocable Transfer Agent  Instructions").  The
          Company  warrants  that no  instruction  other  than  the  Irrevocable
          Transfer Agent Instructions referred to in this Section 5(b), and stop
          transfer  instructions to give effect to Section 2(g) hereof,  will be
          given by the Company to its transfer  agent,  and that the  Securities
          shall otherwise be freely transferable on the books and records of the
          Company as and to the extent  provided in this Agreement and the other
          Transaction  Documents.  If a  Buyer  effects  a sale,  assignment  or
          transfer of the  Securities  in  accordance  with  Section  2(f),  the
          Company  shall  permit the transfer  and shall  promptly  instruct its
          transfer agent to issue one or more  certificates  or credit shares to
          the  applicable  balance  accounts  at DTC in  such  name  and in such
          denominations as specified by such Buyer to effect such sale, transfer
          or  assignment.  In the event that such sale,  assignment  or transfer
          involves  Shares or  Warrant  Shares  sold,  assigned  or  transferred
          pursuant to an  effective  registration  statement or pursuant to Rule
          144,  the  transfer  agent shall issue such  Securities  to the Buyer,
          assignee or transferee,  as the case may be,  without any  restrictive
          legend.  The  Company   acknowledges  that  a  breach  by  it  of  its
          obligations   hereunder  will  cause  irreparable  harm  to  a  Buyer.
          Accordingly,  the  Company  acknowledges  that the remedy at law for a
          breach of its  obligations  under this Section 5(b) will be inadequate
          and  agrees,  in the  event of a breach  or  threatened  breach by the
          Company of the provisions of this Section 5(b),  that a Buyer shall be
          entitled,  in addition to all other  available  remedies,  to an order
          and/or  injunction  restraining  any  breach and  requiring  immediate
          issuance and transfer,  without the necessity of showing economic loss
          and without any bond or other security being required.

          6. CONDITIONS TO THE COMPANY'S OBLIGATION TO SELL.

          The  obligation of the Company  hereunder to issue and sell the Shares
and the  related  Warrants  to each  Buyer  at the  Closing  is  subject  to the
satisfaction,  at  or  before  the  Closing  Date,  of  each  of  the  following
conditions,  provided that these  conditions  are for the Company's sole benefit
and may be waived by the Company at any time in its sole discretion by providing
each Buyer participating in the Closing with prior written notice thereof:

                    (i) Such Buyer shall have executed  each of the  Transaction
          Documents  to  which  it is a  party  and  delivered  the  same to the
          Company.

                    (ii) Such Buyer and each other Buyer shall have delivered to
          the  Company  the  applicable  Purchase  Price for the  Shares and the
          related  Warrants being purchased by such Buyer at the Closing by wire
          transfer  of  immediately   available   funds  pursuant  to  the  wire
          instructions provided by the Company.

                    (iii) The representations and warranties of such Buyer shall
          be true  and  correct  in all  material  respects  (except  for  those
          representations  and  warranties  that are qualified by materiality or
          Material  Adverse  Effect,  which  shall  be true and  correct  in all
          respects)  as of the  date  when  made and as of the  Closing  Date as
          though made at that time (except for  representations  and  warranties
          that speak as of a specific  date,  which shall be true and correct as
          of  such  specified  date),  and  such  Buyer  shall  have  performed,
          satisfied and complied in all material  respects  with the  covenants,
          agreements and conditions  required by this Agreement to be performed,
          satisfied  or  complied  with by such Buyer at or prior to the Closing
          Date.

          7. CONDITIONS TO EACH BUYER'S OBLIGATION TO PURCHASE.

          The obligation of each Buyer  hereunder to purchase the Shares and the
related Warrants at the Closing is subject to the satisfaction, at or before the
Closing  Date,  of  each  of  the  following  conditions,  provided  that  these
conditions  are for each Buyer's sole benefit and may be waived by such Buyer at
any time in its sole  discretion  by providing  the Company  with prior  written
notice thereof.

                    (i) The Company  shall have duly  executed and  delivered to
          such Buyer (a) the Shares being purchased by such Buyer at the Closing
          pursuant to Section 1(a) of this Agreement,  (b) the related  Warrants
          being purchased by such Buyer at the Closing  pursuant to Section 1(a)
          of this Agreement,  and (c) each of the other Transaction Documents to
          which  the  Company  is  a  party  and  such  other   certificates  or
          instruments required to be delivered by it pursuant to the Transaction
          Documents in connection with the Closing.

                    (ii) The Company  shall have  delivered to such Buyer a copy
          of the Irrevocable Transfer Agent Instructions, in the form of Exhibit
          C attached hereto,  which instructions shall have been executed by the
          Company and delivered to and  acknowledged in writing by the Company's
          transfer agent.

                    (iii) Such Buyer  shall have  received  the opinion of Paul,
          Hastings,  Janofsky & Walker LLP, counsel to the Company,  dated as of
          the  Closing  Date,  in  substantially  the form of Exhibit D attached
          hereto.

                    (iv) The Company  shall have  delivered to such Buyer copies
          of (a) the  Certificate  of  Incorporation  of the Company and (b) the
          certificate  of  incorporation  of  Aeolus  Sciences,  Inc.,  each  as
          certified by the  Secretary  of State of the State of Delaware  within
          ten (10) Business Days of the Closing Date.

                    (v) The Company shall have delivered to such Buyer copies of
          certificates  of good  standing  for each of the  Company  and  Aeolus
          Sciences,  Inc.,  each as certified  by the  Secretary of State of the
          State of Delaware within five (5) Business Days of the Closing Date.

                    (vi)  The  Company  shall  have  delivered  to such  Buyer a
          certificate,  executed by the Secretary of the Company and dated as of
          the Closing Date, as to (i) the  resolutions  consistent  with Section
          3(b)  as  adopted  by  the  Company's  board  of  directors  in a form
          reasonably   acceptable  to  such  Buyer,   (ii)  the  Certificate  of
          Incorporation  of the Company,  (iii) the certificate of incorporation
          of Aeolus Sciences, Inc., (iii) the Bylaws of the Company and (iv) the
          bylaws of Aeolus  Sciences,  Inc.,  each as in effect at the  Closing,
          which  certificate  shall be in form and  substance  acceptable to the
          Buyers and shall provide specimen  signatures for each of the officers
          or directors of the Company who execute and deliver this  Agreement or
          any other Transaction Document to be delivered at the Closing by or on
          behalf of the Company (in each case,  pursuant to the authorization of
          the Company's board of directors).

                    (vii) The  representations  and  warranties  of the  Company
          shall be true and correct in all material  respects  (except for those
          representations  and  warranties  that are qualified by materiality or
          Material  Adverse  Effect,  which  shall  be true and  correct  in all
          respects)  as of the date  when  made  and at all  times  through  and
          including  as of the Closing  Date as though made at that time (except
          for  representations  and warranties that speak as of a specific date,
          which  shall be true and  correct as of such  specified  date) and the
          Company shall have  performed,  satisfied and complied in all material
          respects with the covenants, agreements and conditions required by the
          Transaction  Documents to be performed,  satisfied or complied with by
          the  Company at or prior to the  Closing  Date.  Such Buyer shall have
          received  a  certificate,  executed  by the Chief  Executive  Officer,
          President or Vice  President  of the Company,  dated as of the Closing
          Date, to the  foregoing  effect and as to such other matters as may be
          reasonably  requested by such Buyer, in form and substance  acceptable
          to the Buyers.

                    (viii)  The  Common  Stock  (I)  shall  be  designated   for
          quotation  or listed on the  Principal  Market and (II) shall not have
          been  suspended,  as of the Closing  Date, by the SEC or the Principal
          Market from trading on the  Principal  Market nor shall  suspension by
          the  SEC or the  Principal  Market  have  been  threatened,  as of the
          Closing Date, either (A) in writing by the SEC or the Principal Market
          or (B) by falling below the minimum listing  maintenance  requirements
          of the Principal Market.

                    (ix) The  Company  shall  have  obtained  all  governmental,
          regulatory or third party  consents and approvals,  if any,  necessary
          for the sale of the Securities.

                    (x) The  Company  shall  have  delivered  to such Buyer such
          other  documents  relating to the  transactions  contemplated  by this
          Agreement as such Buyer or its counsel may reasonably request.

          8. TERMINATION.  In the event that the Closing shall not have occurred
with respect to a Buyer on or before five (5) Business Days from the date hereof
due to the Company's or such Buyer's failure to satisfy the conditions set forth
in Sections 6 and 7 above (and the  non-breaching  party's failure to waive such
unsatisfied  condition(s)),  the  non-breaching  party  shall have the option to
terminate this  Agreement  with respect to such breaching  party at the close of
business  on such  date  without  liability  of any  party to any  other  party;
provided, however, that if this Agreement is terminated in its entirety pursuant
to this  Section 8 solely as a result of the  Company's  failure to satisfy  the
conditions in Section 7 above,  the Company shall remain  obligated to reimburse
the non-breaching Buyers for the expenses described in Section 4(g) above.

          9. MISCELLANEOUS.

                    (a) Governing Law;  Jurisdiction;  Jury Trial. All questions
          concerning the construction,  validity, enforcement and interpretation
          of this Agreement  shall be governed by the internal laws of the State
          of New York, without giving effect to any choice of law or conflict of
          law  provision or rule  (whether of the State of New York or any other
          jurisdictions)  that would  cause the  application  of the laws of any
          jurisdictions  other  than the State of New York.  Each  party  hereby
          irrevocably  submits to the  exclusive  jurisdiction  of the state and
          federal  courts  sitting  in The  City of New  York,  the  borough  of
          Manhattan,  for  the  adjudication  of  any  dispute  hereunder  or in
          connection  herewith or with any  transaction  contemplated  hereby or
          discussed herein,  and hereby  irrevocably  waives,  and agrees not to
          assert in any suit,  action or  proceeding,  any claim  that it is not
          personally  subject to the  jurisdiction of any such court,  that such
          suit, action or proceeding is brought in an inconvenient forum or that
          the venue of such suit,  action or proceeding is improper.  Each party
          hereby  irrevocably waives personal service of process and consents to
          process being served in any such suit, action or proceeding by mailing
          a copy  thereof to such party at the  address  for such  notices to it
          under this  Agreement  and agrees that such service  shall  constitute
          good and  sufficient  service of process and notice  thereof.  Nothing
          contained  herein  shall be  deemed  to limit in any way any  right to
          serve  process  in any manner  permitted  by law.  EACH  PARTY  HEREBY
          IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE, AND AGREES NOT TO REQUEST, A
          JURY  TRIAL  FOR  THE  ADJUDICATION  OF ANY  DISPUTE  HEREUNDER  OR IN
          CONNECTION  WITH OR ARISING OUT OF THIS  AGREEMENT OR ANY  TRANSACTION
          CONTEMPLATED HEREBY.

                    (b)  Counterparts.  This Agreement may be executed in two or
          more identical counterparts,  all of which shall be considered one and
          the same agreement and shall become effective when  counterparts  have
          been signed by each party and  delivered to the other party;  provided
          that a facsimile signature shall be considered due execution and shall
          be binding upon the  signatory  thereto with the same force and effect
          as if the signature were an original, not a facsimile signature.

                    (c)  Headings.  The  headings  of  this  Agreement  are  for
          convenience  of  reference  and shall not form part of, or affect  the
          interpretation of, this Agreement.

                    (d)  Severability.  If any provision of this Agreement shall
          be invalid or  unenforceable in any  jurisdiction,  such invalidity or
          unenforceability  shall not affect the validity or  enforceability  of
          the remainder of this Agreement in that  jurisdiction  or the validity
          or  enforceability  of any  provision  of this  Agreement in any other
          jurisdiction.

                    (e) Entire  Agreement;  Amendments.  This  Agreement and the
          other Transaction  Documents supersede all other prior oral or written
          agreements  between the Buyers,  the  Company,  their  affiliates  and
          Persons  acting on their behalf with respect to the matters  discussed
          herein,  and this Agreement,  the other Transaction  Documents and the
          instruments   referenced   herein  and  therein   contain  the  entire
          understanding  of the  parties  with  respect to the  matters  covered
          herein and therein  and,  except as  specifically  set forth herein or
          therein,  neither the Company nor any Buyer makes any  representation,
          warranty,  covenant or  undertaking  with respect to such matters.  No
          provision of this Agreement may be amended other than by an instrument
          in  writing  signed  by  the  Company  and  the  holders  of at  least
          two-thirds of the aggregate number of Shares and Warrant Shares issued
          and issuable  under the Warrants,  and any amendment to this Agreement
          made in conformity  with the  provisions of this Section 9(e) shall be
          binding on all Buyers and  holders of  Securities  as  applicable.  No
          provision  hereof may be waived other than by an instrument in writing
          signed  by the party  against  whom  enforcement  is  sought.  No such
          amendment  shall be  effective  to the extent  that it applies to less
          than all of the holders of the applicable Securities then outstanding.
          No  consideration  shall be  offered or paid to any Person to amend or
          consent to a waiver or  modification  of any  provision  of any of the
          Transaction Documents unless the same consideration also is offered to
          all of the parties to the Transaction Documents,  holders of Shares or
          holders of the Warrants, as the case may be.

                    (f)  Notices.  Any  notices,   consents,  waivers  or  other
          communications  required or  permitted  to be given under the terms of
          this  Agreement  must be in  writing  and will be  deemed to have been
          delivered:  (i) upon receipt,  when  delivered  personally;  (ii) upon
          receipt, when sent by facsimile (provided confirmation of transmission
          is  mechanically or  electronically  generated and kept on file by the
          sending  party);  or (iii)  one  Business  Day after  deposit  with an
          overnight  courier  service,  in each case  properly  addressed to the
          party to receive the same.  The addresses  and  facsimile  numbers for
          such communications shall be:

                           If to the Company:

                                    Aeolus Pharmaceuticals, Inc.
                                    26361 Crown Valley Parkway, Suite 150
                                    Mission Viejo, California 92691
                                    Telephone:       (949) 481-9825
                                    Facsimile:       (949) 481-9829
                                    Attention:       John L. McManus, President

                           with a copy to:

                                    Paul, Hastings, Janofsky & Walker LLP
                                     4747 Executive Drive, 12th Floor
                                    San Diego, California  92121
                                    Telephone:       (858) 458-3036
                                    Facsimile:       (858) 458-3136
                                    Attention:       Leigh P. Ryan

                           If to the Transfer Agent:

                                    American Stock Transfer and Trust Company
                                    6201 15th Avenue
                                    Brooklyn, New York  11219
                                    Telephone:       (718) 921-8247
                                    Facsimile:       (718) 921-8323
                                    Attention:       Wilbert Myles

                    If to a Buyer, to its address and facsimile number set forth
          on the Schedule of Buyers, with copies to such Buyer's representatives
          as set forth on the Schedule of Buyers,

                           with a copy (for informational purposes only) to:

                                    Xmark Opportunity Partners, LLC
                                    90 Grove Street, Suite 201
                                    Ridgefield, Connecticut  06877
                                    Telephone:       (203) 244-9503
                                    Facsimile:       (203) 438-9949
                                    Attention:       Mitchell D. Kaye

                                    and

                                    Lowenstein Sandler PC
                                    1251 Avenue of the Americas, 18th Floor
                                    New  York, New York  10020
                                    Telephone:       (212) 204-8688
                                    Facsimile:       (973) 597-2507
                                    Attention:       Steven E. Siesser

                    or to such other address and/or  facsimile  number and/or to
          the  attention  of  such  other  Person  as the  recipient  party  has
          specified  by written  notice  given to each other party five (5) days
          prior to the  effectiveness  of such change.  Written  confirmation of
          receipt (A) given by the recipient of such notice,  consent, waiver or
          other communication,  (B) mechanically or electronically  generated by
          the sender's  facsimile machine  containing the time, date,  recipient
          facsimile  number and an image of the first page of such  transmission
          or (C) provided by an overnight  courier  service  shall be rebuttable
          evidence of personal service,  receipt by facsimile or receipt from an
          overnight courier service in accordance with clause (i), (ii) or (iii)
          above, respectively.

                    (g) Successors and Assigns.  This Agreement shall be binding
          upon and inure to the  benefit  of the  parties  and their  respective
          successors and assigns,  including any purchasers of the Shares or the
          Warrants. The Company shall not assign this Agreement or any rights or
          obligations hereunder without the prior written consent of the holders
          of at least  two-thirds  of the Shares and Warrant  Shares  issued and
          issuable  under  the  Warrants,  including  by  way  of a  Fundamental
          Transaction  (unless the Company is in compliance  with the applicable
          provisions  governing  Fundamental   Transactions  set  forth  in  the
          Warrants).  Except as set forth in Section  2(f) above with respect to
          the  Warrant  Shares,  a Buyer may  assign  some or all of its  rights
          hereunder  without  the  consent of the  Company,  in which event such
          assignee shall be deemed to be a Buyer  hereunder with respect to such
          assigned  rights and shall enter into a joinder to this  Agreement and
          shall become  subject to the terms and  conditions  of this  Agreement
          applicable to a Buyer with respect to such rights assigned to it.

                    (h) No Third Party Beneficiaries. This Agreement is intended
          for the benefit of the parties hereto and their  respective  permitted
          successors  and  assigns,  and is not for the  benefit of, nor may any
          provision hereof be enforced by, any other Person.

                    (i)  Survival.  Unless this  Agreement is  terminated  under
          Section 8, the  representations  and warranties of the Company and the
          Buyers contained in Sections 2 and 3, and the agreements and covenants
          set forth in Sections 4, 5 and 9 shall survive the Closing. Each Buyer
          shall be  responsible  only for its own  representations,  warranties,
          agreements and covenants hereunder.

                    (j) Further Assurances.  Each party shall do and perform, or
          cause to be done and performed,  all such further acts and things, and
          shall  execute and deliver  all such other  agreements,  certificates,
          instruments and documents,  as any other party may reasonably  request
          in order to carry out the intent and  accomplish  the purposes of this
          Agreement  and  the  consummation  of  the  transactions  contemplated
          hereby.

                    (k) Indemnification.

                              (i) In consideration of each Buyer's execution and
                    delivery of the  Transaction  Documents  and  acquiring  the
                    Securities   thereunder  and  in  addition  to  all  of  the
                    Company's other obligations under the Transaction Documents,
                    the  Company  shall  defend,  protect,  indemnify  and  hold
                    harmless each Buyer and each other holder of the  Securities
                    and all of their stockholders,  partners, members, officers,
                    directors,  employees  and direct or indirect  investors and
                    any   of   the   foregoing    Persons'   agents   or   other
                    representatives   (including,   without  limitation,   those
                    retained in connection with the transactions contemplated by
                    this Agreement)  (collectively,  the "Indemnitees") from and
                    against  any and  all  actions,  causes  of  action,  suits,
                    claims,  losses,  costs,  penalties,  fees,  liabilities and
                    damages, and expenses in connection therewith  (irrespective
                    of whether any such  Indemnitee is a party to the action for
                    which  indemnification  hereunder is sought),  and including
                    reasonable    attorneys'   fees   and   disbursements   (the
                    "Indemnified Liabilities"),  incurred by any Indemnitee as a
                    result  of,  or  arising  out  of,  or  relating  to (a) any
                    misrepresentation   or  breach  of  any   representation  or
                    warranty made by the Company in the Transaction Documents or
                    any other  certificate,  instrument  or  document  delivered
                    hereby  or  thereby  or (b)  any  breach  of  any  covenant,
                    agreement  or  obligation  of the Company  contained  in the
                    Transaction  Documents or any other certificate,  instrument
                    or document delivered hereby or thereby.  The amount paid or
                    payable  by  an  Indemnitee  as  a  result  any  Indemnified
                    Liability (or action in respect  thereof) shall be deemed to
                    include,  for purposes of this Section 9(k),  any reasonable
                    legal or other expenses  reasonably and actually incurred by
                    such   Indemnitee  in  connection  with   investigating   or
                    defending or preparing to defend any such action or claim.

                              (ii) Promptly after receipt by an Indemnitee under
                    this Section 9(k) of notice of any claim or the commencement
                    of any action,  such Indemnitee shall, if a claim in respect
                    thereof is to be made against the  indemnifying  party under
                    this  Section  9(k),  notify  the  Company in writing of the
                    claim or the commencement of that action; provided, however,
                    that the failure to notify the Company shall not relieve the
                    Company  from any  liability  which it may have  under  this
                    Section  9(k)  except  to the  extent  the  Company,  in its
                    capacity as the  indemnifying  party, has been prejudiced by
                    such  failure.  If any such claim or action shall be brought
                    against  an  Indemnitee,  and it shall  notify  the  Company
                    thereof,  the  Company  shall  be  entitled  to  participate
                    therein  and,  to the extent  that it wishes,  to assume the
                    defense   thereof   with   counsel   satisfactory   to  such
                    Indemnitee.  After notice from the Company to the applicable
                    Indemnitee  of its  election  to assume the  defense of such
                    claim or  action,  the  Company  shall not be liable to such
                    Indemnitee  under this  Section  9(k) for any legal or other
                    expenses   subsequently   incurred  by  such  Indemnitee  in
                    connection  with the defense  thereof other than  reasonable
                    costs of  investigation.  The  Company,  in its  capacity as
                    indemnifying party, shall not:

                                        (x) without the prior written consent of
                              each  applicable  Indemnitee  (which consent shall
                              not  be  unreasonably  withheld,   conditioned  or
                              delayed),  settle or  compromise or consent to the
                              entry of any judgment  with respect to any pending
                              or threatened claim, action, suit or proceeding in
                              respect of which  indemnification  or contribution
                              may be  sought  hereunder  (whether  or  not  such
                              Indemnitees  are  actual or  potential  parties to
                              such  claim or  action)  unless  such  settlement,
                              compromise  or consent  includes an  unconditional
                              release of each such Indemnitee from all liability
                              arising  out  of  such  claim,   action,  suit  or
                              proceeding, or

                                        (y) be liable for any  settlement of any
                              such action  effected  without its written consent
                              (which consent shall not be unreasonably withheld,
                              conditioned  or delayed),  but if settled with its
                              written  consent  or if there be a final  judgment
                              for the plaintiff in any such action, the Company,
                              in its capacity as the indemnifying  party, agrees
                              to indemnify  and hold  harmless  each  applicable
                              Indemnitee  from and against any loss or liability
                              by reason of such settlement or judgment.

                              (iii) If the indemnification  provided for in this
                    Section  9(k)  shall  for  any  reason  be   unavailable  or
                    insufficient  to hold  harmless an  Indemnitee in respect of
                    any  Indemnified  Liability (or action in respect  thereof),
                    the  Company,  in its  capacity as the  indemnifying  party,
                    shall, in lieu of indemnifying  such Indemnitee,  contribute
                    to the amount paid or payable by such Indemnitee as a result
                    of  such   Indemnified   Liability  (or  action  in  respect
                    thereof),  in such  proportion as is  appropriate to reflect
                    the  relative  fault of the Company on the one hand and each
                    applicable Indemnitee on the other.

                    (l) No  Strict  Construction.  The  language  used  in  this
          Agreement  will be deemed to be the language  chosen by the parties to
          express their mutual intent, and no rules of strict  construction will
          be applied against any party.

                    (m) Remedies.  Each Buyer and each holder of the  Securities
          shall  have all  rights  and  remedies  set  forth in the  Transaction
          Documents  and all rights and  remedies  which such  holders have been
          granted at any time under any other  agreement  or contract and all of
          the rights which such  holders  have under any law. Any Person  having
          any rights under any provision of this Agreement  shall be entitled to
          enforce  such  rights  specifically  (without  posting a bond or other
          security), to recover damages by reason of any breach of any provision
          of this  Agreement  and to exercise all other  rights  granted by law.
          Furthermore, the Company recognizes that in the event that it fails to
          perform, observe, or discharge any or all of its obligations under the
          Transaction  Documents,  any remedy at law may prove to be  inadequate
          relief to the  Buyers.  The Company  therefore  agrees that the Buyers
          shall be entitled to seek temporary and permanent injunctive relief in
          any such case  without the  necessity  of proving  actual  damages and
          without posting a bond or other security.

                    (n)  Rescission  and   Withdrawal   Right.   Notwithstanding
          anything  to the  contrary  contained  in (and  without  limiting  any
          similar provisions of) the Transaction  Documents,  whenever any Buyer
          exercises  a right,  election,  demand or option  under a  Transaction
          Document  and  the  Company  does  not  timely   perform  its  related
          obligations  within the periods therein provided,  then such Buyer may
          rescind or  withdraw,  in its sole  discretion  from time to time upon
          written notice to the Company, any relevant notice, demand or election
          in  whole or in part  without  prejudice  to its  future  actions  and
          rights.

                    (o) Payment Set Aside.  To the extent that the Company makes
          a payment or  payments to the Buyers  hereunder  or pursuant to any of
          the other  Transaction  Documents  or the Buyers  enforce or  exercise
          their rights hereunder or thereunder,  and such payment or payments or
          the proceeds of such  enforcement  or exercise or any part thereof are
          subsequently  invalidated,  declared to be fraudulent or preferential,
          set  aside,  recovered  from,  disgorged  by  or  are  required  to be
          refunded,  repaid or  otherwise  restored to the  Company,  a trustee,
          receiver  or any  other  Person  under  any  law  (including,  without
          limitation,  any bankruptcy law, foreign, state or federal law, common
          law or  equitable  cause of  action),  then to the  extent of any such
          restoration the obligation or part thereof  originally  intended to be
          satisfied  shall be revived and  continued in full force and effect as
          if such  payment had not been made or such  enforcement  or setoff had
          not occurred.

                    (p)  Independent  Nature of Buyers'  Obligations and Rights.
          The  obligations  of each Buyer  under any  Transaction  Document  are
          several and not joint with the obligations of any other Buyer,  and no
          Buyer  shall  be  responsible  in any way for the  performance  of the
          obligations of any other Buyer under any Transaction Document. Nothing
          contained herein or in any other Transaction  Document,  and no action
          taken by any  Buyer  pursuant  hereto or  thereto,  shall be deemed to
          constitute the Buyers as, and the Company acknowledges that the Buyers
          do not so constitute, a partnership,  an association,  a joint venture
          or any other kind of entity,  or create a presumption  that the Buyers
          are in any way acting in concert or as a group,  and the Company  will
          not  assert any such claim  with  respect to such  obligations  or the
          transactions contemplated by the Transaction Documents and the Company
          acknowledges  that the  Buyers are not acting in concert or as a group
          with respect to such obligations or the  transactions  contemplated by
          the Transaction  Documents.  The Company  acknowledges  and each Buyer
          confirms that it has independently  participated in the negotiation of
          the transaction contemplated hereby with the advice of its own counsel
          and advisors.  Each Buyer shall be entitled to  independently  protect
          and enforce  its rights,  including,  without  limitation,  the rights
          arising  out  of  this  Agreement  or out  of  any  other  Transaction
          Documents,  and it shall not be  necessary  for any other  Buyer to be
          joined as an additional party in any proceeding for such purpose.

                            [Signature Pages Follow.]







                 SIGNATURE PAGE TO SECURITIES PURCHASE AGREEMENT

          IN WITNESS  WHEREOF,  each Buyer and the  Company  have  caused  their
respective  signature  page to this  Securities  Purchase  Agreement  to be duly
executed as of the date first written above.


                  COMPANY:

                  AEOLUS PHARMACEUTICALS, INC.



                  By:
                     ----------------------------------------------
                     Name:  John L. McManus
                     Title: President







          IN WITNESS  WHEREOF,  each Buyer and the  Company  have  caused  their
respective  signature  page to this  Securities  Purchase  Agreement  to be duly
executed as of the date first written above.


BUYERS:


                  XMARK OPPORTUNITY FUND, L.P.
                  By:    XMARK OPPORTUNITY GP, LLC, its General Partner
                  By:    XMARK OPPORTUNITY PARTNERS, LLC, its Sole Member
                  By:    XMARK CAPITAL PARTNERS, LLC, its Managing Member



                  By:
                      -------------------------------------------------------
                      Name:     Mitchell D. Kaye
                      Title:    Co-Managing Member


                  XMARK OPPORTUNITY FUND, LTD.
                  By:    XMARK OPPORTUNITY MANAGER, LLC, its Investment Manager
                  By:    XMARK OPPORTUNITY PARTNERS, LLC, its Sole Member
                  By:    XMARK CAPITAL PARTNERS, LLC, its Managing Member



                   By:
                      -------------------------------------------------------
                      Name:     Mitchell D. Kaye
                      Title:    Co-Managing Member













                               SCHEDULE OF BUYERS


(1)                              (2)                                   (3)         (4)               (5)          (6)
                                                                                                


                                 Address and                                                                      Legal
                                 Facsimile Number                      Number of    Number of         Purchase    Representative's
Purchaser                        (Jurisdiction)                        Shares       Warrant Shares    Price       Address and
                                                                                                                  Facsimile Number
                                                                                                                  (if different
                                                                                                                   than in column
                                                                                                                   (2))





Xmark Opportunity Fund, L.P.     c/o Xmark Opportunity Partners, LLC   1,875,000   4,687,500         $525,000.00
                                 90 Grove Street
                                 Suite 201
                                 Ridgefield, CT  06877
                                 Telephone:  (203) 244-9503
                                 Facsimile:  (203) 438-9949
                                 Attention:  Mitchell D. Kaye
                                 (Delaware)

Xmark Opportunity Fund, Ltd.     c/o Xmark Opportunity Partners, LLC   3,482,143   8,705,357        $975,000.00
                                 90 Grove Street
                                 Suite 201
                                 Ridgefield, CT  06877
                                 Telephone:  (203) 244-9503
                                 Facsimile:  (203) 438-9949
                                 Attention:  Mitchell D. Kaye
                                 (Cayman Islands)

                                 Total                                 5,357,143   13,392,857       $1,500,000.00












                                    EXHIBITS

Exhibit A         Form of Warrant
Exhibit B         Form of Registration Rights Agreement
Exhibit C         Form of Irrevocable Transfer Agent Instructions
Exhibit D         Form of Opinion of Company's Counsel

                                    SCHEDULES

Schedule 3(a)              Organization and Qualification
Schedule 3(b)              Authorization; Enforcement; Validity
Schedule 3(d)              No Conflicts
Schedule 3(e)              Consents and Filings
Schedule 3(k)              Absence of Certain Changes
Schedule 3(o)              Sarbanes-Oxley Act
Schedule 3(p)              Transactions with Affiliates
Schedule 3(q)              Equity Capitalization
Schedule 3(r)              Indebtedness and Other Contracts
Schedule 3(t)              Insurance
Schedule 3(u)              Employee Relations
Schedule 3(v)              Title
Schedule 3(w)              Intellectual Property Rights
Schedule 3(z)              Internal Accounting and Disclosure Controls
Schedule 3(gg)             Placement Agents