UNITED STATES


                       SECURITIES AND EXCHANGE COMMISSION


                             WASHINGTON, D.C. 20549


                                   ----------


                                 SCHEDULE 13G/A

                                Amendment No. 1

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934


             Information to be included in statements filed pursuant
           to Rules 13d-1(b), (c) and (d) and amendments thereto filed
                            pursuant to Rule 13d-2(b)

                                   ----------

                               LUMINEX CORPORATION
                                (Name of Issuer)

                                  Common Stock
                         (Title of Class of Securities)

                                   55027E 10 2
                                 (Cusip Number)

                                December 31, 2001
             (Date of Event Which Requires Filing of this Statement)

                                   ----------

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

                  [ ]  Rule 13d-1(b)

                  [ ]  Rule 13d-1(c)

                  [X]  Rule 13d-1(d)

The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



                                Page 1 of 5 Pages


CUSIP No. 55027E 10 2             SCHEDULE 13G
                             (cover page continued)

1.   NAME OF REPORTING PERSON

                  Mark B. Chandler

     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP *

                                                                    (A) [ ]
                                                                    (B) [ ]

3.   SEC USE ONLY

4.   CITIZENSHIP OR PLACE OF ORGANIZATION

                  United States

                                            5.       SOLE VOTING POWER

                                                     300,000
NUMBER OF
SHARES                                      6.       SHARED VOTING POWER
BENEFICIALLY
OWNED BY                                             3,604,255
EACH
REPORTING PERSON                            7.       SOLE DISPOSITIVE POWER

                                                     300,000

                                            8.       SHARED DISPOSITIVE POWER

                                                     3,604,255


9.   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  3,904,255

10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  [X]

                  100,000 shares are held by Mrs. Chandler as trustee in a trust
                  for her benefit and 200,000 shares held by Mrs. Chandler as
                  her separate property.

11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  13.6 %

12.  TYPE OF REPORTING PERSON

     IN



                                Page 2 of 5 Pages


                                  SCHEDULE 13G


ITEM 1(A).      NAME OF ISSUER: Luminex Corporation

ITEM 1(B).      ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

                12212 Technology Blvd., Austin, Texas 78727

ITEM 2(A).      NAME OF PERSON FILING: Mark B. Chandler, Ph.D.

ITEM 2(B).      ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:

                12212 Technology Blvd., Austin, Texas 78727

ITEM 2(C).      CITIZENSHIP: United States (Texas)

ITEM 2(D).      TITLE OF CLASS OR SECURITIES: Common Stock, $0.001 par value

ITEM 2(E).      CUSIP NUMBER: 55027E 10 2

ITEM 3.         IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B) OR
                13D-2(B),

                (A)  [ ]  BROKER OR DEALER REGISTERED UNDER THE ACT

                (B)  [ ]  BANK AS DEFINED IN SECTION 3 (A) (6) OF THE ACT

                (C)  [ ]  INSURANCE COMPANY AS DEFINED IN SECTION 3 (A) (19) OF
                          THE ACT

                (D)  [ ]  INVESTMENT COMPANY REGISTERED UNDER SECTION 8 OF THE
                          INVESTMENT COMPANY ACT

                (E)  [ ]  INVESTMENT ADVISER REGISTERED UNDER SECTION 203 OF THE
                          INVESTMENT ADVISERS ACT OF 1940

                (F)  [ ]  EMPLOYEE BENEFIT PLAN, PENSION FUND WHICH IS SUBJECT
                          TO THE PROVISIONS OF THE EMPLOYEE RETIREMENT INCOME
                          SECURITY ACT OF 1974 OR ENDOWMENT FUND; SEE SECTION
                          240.13D- (B) (1) (II) (F)

                (G)  [ ]  PARENT HOLDING COMPANY, IN ACCORDANCE WITH SECTION
                          240.13D-1 (B) (II) (G); SEE ITEM 7

                (H)  [ ]  GROUP, IN ACCORDANCE WITH SECTION 240.13D-1 (B) (1)
                          (II) (H)

ITEM 4.         OWNERSHIP:

                (A)  AMOUNT BENEFICIALLY OWNED: 3,904,255 shares of which
                                                150,000 shares are owned
                                                directly, 3,133,702 shares owned
                                                jointly, 100,000 shares are held
                                                in trust for the benefit of Dr.
                                                Chandler of which Dr. Chandler
                                                is the Trustee, 50,000 shares
                                                are held in trust for the
                                                benefit of his daughter of which
                                                Dr. Chandler is the Trustee and
                                                470,553 shares of Common Stock
                                                subject to vested and
                                                immediately exercisable stock
                                                options.

                (B)  PERCENT OF CLASS: 13.6 %



                                Page 3 of 5 Pages


                                  SCHEDULE 13G


                (C)  NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS:

                     (I)   SOLE POWER TO VOTE OR TO DIRECT THE VOTE:

                                    300,000

                     (II)  SHARED POWER TO VOTE OR TO DIRECT THE VOTE:

                                    3,604,255

                     (III) SOLE POWER TO DISPOSE OR TO DIRECT THE DISPOSITION
                           OF:

                                    300,000

                     (IV)  SHARED POWER TO DISPOSE OR TO DIRECT THE DISPOSITION
                           OF:

                                    3,604,255


ITEM 5.         OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

                     IF THIS STATEMENT IS BEING FILED TO REPORT THE FACT THAT AS
                     OF THE DATE HEREOF THE REPORTING PERSON HAS CEASED TO BE
                     THE BENEFICIAL OWNER OF MORE THAN FIVE PERCENT OF THE CLASS
                     OF SECURITIES, CHECK THE FOLLOWING [ ].

                     Not applicable.

ITEM 6.         OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

                     Not applicable.

ITEM 7.         IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
                ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
                COMPANY.

                     Not applicable.

ITEM 8.         IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

                     Not applicable.

ITEM 9.         NOTICE OF DISSOLUTION OF GROUP.

                    Not applicable.

ITEM 10.        CERTIFICATION.

                           By signing below I certify that, to the best of my
                knowledge and belief, the securities referred to above were not
                acquired and are not held for the purpose of or with the effect
                of changing or influencing the control of the issuer of the
                securities and were not acquired and are not held in connection
                with or as a participant in any transaction having that purpose
                or effect.



                                Page 4 of 5 Pages


                                  SCHEDULE 13G

                                    SIGNATURE

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.





                                                /s/ Mark B. Chandler
                                       -----------------------------------------
                                       Mark B. Chandler

Date: 7 February 2002



                                Page 5 of 5 Pages