SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   ----------

                                 SCHEDULE 13G/A
                                 (Rule 13d-102)

        INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES
       13D-1(b),(c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE
                                      13d-2
                               (Amendment No. 4)*


                            NEOSE TECHNOLOGIES, INC.
                                (Name of Issuer)

                     Common Stock, par value $.01 per share
                         (Title of Class of Securities)

                                    640522108
                                 (CUSIP Number)


                                February 13, 2006
             (Date of Event Which Requires Filing of this Statement)

    Check the appropriate box to designate the rule pursuant to which this
    Schedule is filed.

    [ ] Rule 13d-1(b)

    [X] Rule 13d-1(c)

    [ ] Rule 13d-1(d)



*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 or  otherwise  subject to the  liabilities  of that  section of the Act but
shall be subject to all other provisions of the Act (however, see the Notes).







CUSIP No. 640522108                    13G                     Page 2 of 6 Pages
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1.  NAME OF REPORTING PERSONS
    I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
    George W. Haywood
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2.  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
                                                      (a) [ ]
                                                      (b) [ ]
--------------------------------------------------------------------------------

3.  SEC USE ONLY
--------------------------------------------------------------------------------

4.  CITIZENSHIP OR PLACE OF ORGANIZATION
    U.S.A
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  NUMBER OF         5.      SOLE VOTING POWER                      1,466,545 (1)
  SHARES
  BENEFICIALLY      ------------------------------------------------------------
  OWNED BY          6.      SHARED VOTING POWER                    208,000 (2)
  EACH
  REPORTING         ------------------------------------------------------------
  PERSON WITH       7.      SOLE DISPOSITIVE POWER                 1,466,545 (1)

                    ------------------------------------------------------------
                    8.      SHARED DISPOSITIVE POWER               208,000 (2)
--------------------------------------------------------------------------------

9.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
    1,674,545
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10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE
    INSTRUCTIONS)                                                     [ ]
--------------------------------------------------------------------------------

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
    5.1%
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12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
    IN
--------------------------------------------------------------------------------

(1) Includes 3,545 shares owned by children.
(2) Represents shares owned by spouse.

                                       2




Item 1(a).    Name of Issuer:

              Neose Technologies, Inc.

Item 1(b).    Address of Issuer's Principal Executive Offices:

              102 Witmer Road, Horsham, Pennsylvania 19044

Item 2(a).    Name of Person Filing:

              George W. Haywood

Item 2(b).    Address of Principal Business Office or, if none, Residence:

              c/o Cronin & Vris, LLP, 380 Madison Avenue, 24th Floor, New York,
              New York 10017

Item 2(c).    Citizenship:

              U.S.A

Item 2(d).    Title of Class of Securities:

              Common Stock, par value $.01 per share

Item 2(e).    CUSIP Number

              640522108

Item 3.       If This Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b)
              or (c), Check Whether the Person Filing is a:

              (a)[ ]  Broker or dealer registered under Section 15 of the
                      Exchange Act.

              (b)[ ]  Bank as defined in Section 3(a) (6) of the Exchange Act.

              (c)[ ]  Insurance company as defined in Section 3(a)(19) of the
                      Exchange Act.

              (d)[ ]  Investment company registered under Section 8 of the
                      Investment Company Act.

              (e)[ ]  An investment adviser in accordance with Rule 13d-1(b)(1)
                      (ii)(E).

              (f)[ ]  An employee benefit plan or endowment fund in accordance
                      with Rule 13d-1(b)(1)(ii)(F).

              (g)[ ]  A parent holding company or control person in accordance
                      with Rule 13d-1(b)(1)(ii)(G).

              (h)[ ]  A savings association as defined in Section 3 (b) of the
                      Federal Deposit Insurance Act.

                                       3



              (i)[ ]  A church plan that is excluded from the definition of an
                      investment  company under Section 3(c)(14) of the
                      Investment Company Act.

              (j)[ ]  Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

Item 4.       Ownership.

           Provide the following  information regarding the aggregate number and
           percentage of the class of securities of the issue identified in Item
           1.

       (a) Amount Beneficially Owned:                                  1,674,545

       (b) Percent of Class:                                                5.1%

       (c) Number of shares as to which such person has:

          (i) sole power to vote or to direct the vote:                1,466,545

          (ii)shared power to vote or to direct vote:                    208,000

          (iii) sole power to dispose or to direct the disposition of: 1,466,545

          (iv) shared power to dispose or to direct the disposition of:  208,000

Item 5.       Ownership of Five Percent or Less of a Class.

              Not applicable.

Item 6.       Ownership of More than Five Percent on Behalf of Another Person.

              Included   as  shares  for  which  there  exist  sole  voting  and
              dispositive  power are 3,545 shares owned by Mr.  Haywood's  minor
              children,  which  children  would have the right to the receipt of
              dividends from, and the proceeds from the sale of, such shares.

              Included  as shares  for  which  there  exist  shared  voting  and
              dispositive  power  are  208,000  shares  owned  by Mr.  Haywood's
              spouse,  which  spouse  would  have the  right to the  receipt  of
              dividends from, and proceeds for the sale of, such shares.

Item 7.       Identification and Classification of the Subsidiary Which Acquired
              the Security Being Reported On By the Parent Holding Company or
              Control Person.

              Not applicable.

Item 8.       Identification and Classification of Members of the Group.

              Not applicable.


                                       4



Item 9.       Notice of Dissolution of Group.

              Not applicable.

Item 10.      Certification.

              By signing  below I certify  that, to the best of my knowledge and
              and belief, the securities referred to above were not acquired and
              are not held for the  purpose of or with the effect of changing or
              influencing  the control of the issuer of the  securities and were
              not  acquired  and  are  not  held  in  connection  with  or  as a
              participant in any transaction having that purpose or effect.



                                       5



                                    SIGNATURE

       After  reasonable  inquiry and to the best of my knowledge and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.


                                          February 14, 2006
                                    -----------------------------
                                              (Date)


                                        /s/George W. Haywood
                                    -----------------------------
                                            (Signature)


                                          George W. Haywood
                                    -----------------------------
                                            (Name/Title)



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