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Applied Molecular Transport Reports First Quarter 2023 Financial Results

SOUTH SAN FRANCISCO, Calif., May 11, 2023 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (Nasdaq: AMTI) (AMT), a biopharmaceutical company, today reported financial results for the first quarter ended March 31, 2023.

Recent Business Highlights

  • Engaged MTS Health Partners, L.P. as advisors in a process to explore strategic alternatives for the company
  • Appointed Shawn Cross to serve as chief executive officer and board chair
  • Tahir Mahmood, Ph.D., co-founder and former CEO remains a member of the board and retained as a consultant

Financial Results for the First Quarter Ended March 31, 2023

Research and development (R&D) expenses. Total R&D expenses for the first quarter of 2023 were $13.0 million, compared to $31.2 million for the same period in 2022. The overall decrease was attributable to our restructuring of operations, related reductions in workforce implemented in March 2023 and halting all research and development activities.

General and administrative (G&A) expenses. Total G&A expenses for the first quarter of 2023 were $6.8 million, compared to $11.3 million for the same period in 2022. The overall decrease was attributable to our restructuring of operations and related reductions in workforce implemented in March 2023.

Restructuring, impairment, and related charges. Total restructuring, impairment, and related charges for the first quarter of 2023 were $8.7 million as the company halted all research and development activities, commenced the close out of existing programs and reduced its workforce by approximately 82%. There were no restructuring, impairment, and related charges recorded for the same period in 2022.

Net loss. Net loss for the first quarter of 2023 was $27.9 million, compared to $42.6 million for the same period in 2022. Operating expenses for the first quarter of 2023 were $28.5 million and interest income was $0.6 million.

Cash and cash equivalents. As of March 31, 2023, cash and cash equivalents were $41.8 million. The company believes its cash and cash equivalents will be sufficient to allow the company to fund its current operating plan for at least twelve months.

About Applied Molecular Transport Inc.

AMT is a biopharmaceutical company that has developed novel oral biologic product candidates, by leveraging its technology platform to design biologic product candidates in patient-friendly oral dosage forms. AMT’s product candidates are designed to precisely target the relevant pathophysiology of the disease. AMT’s proprietary technology platform is incorporated in its product candidates, exploiting existing natural cellular trafficking pathways to drive the active transport of diverse therapeutic modalities across the IE barrier. Active transport is an efficient mechanism that utilizes the cell’s own machinery to transport materials across the IE barrier. The company has halted all research and development activities and commenced a process to explore strategic alternatives.

For additional information on AMT, please visit

Forward-Looking Statements

This press release contains forward-looking statements as that term is defined in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Such forward-looking statements involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements including statements relating to AMT’s plans, expectations, forecasts and future events. Such forward-looking statements include, but are not limited to, statements regarding the ability of AMT to enter into a strategic transaction and sufficiency of AMT’s cash resources. In some cases, you can identify forward- looking statements by terminology such as “believe,” “estimate,” “intend,” “may,” “plan,” “potentially,” “will,” “expect,” “enable,” “likely” or the negative of these terms or other similar expressions. We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. Actual events, trends or results could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements based on various factors. Information regarding the foregoing and additional risks may be found in the section entitled “Risk Factors” in AMT’s Annual and Quarterly Reports on Form 10-K and 10-Q filed with the Securities and Exchange Commission (the “SEC”), and AMT’s future reports to be filed with the SEC. These forward-looking statements are made as of the date of this press release, and AMT assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law.

Applied Molecular Transport Inc.
Condensed Balance Sheets
(in thousands)

 March 31,
 December 31,
Current assets:   
Cash and cash equivalents$41,771  $61,145 
Prepaid expenses 1,929   2,688 
Other current assets 370   186 
Long-lived assets held for sale 2,250    
Total current assets 46,320   64,019 
Property and equipment, net 2,790   8,183 
Operating lease right-of-use assets 32,086   33,222 
Finance lease right-of-use assets 688   584 
Restricted cash 916   916 
Other assets 495   522 
Total assets$83,295  $107,446 
Liabilities and stockholders’ equity   
Current liabilities:   
Accounts payable$871  $1,583 
Accrued expenses 10,990   8,660 
Lease liabilities, operating lease - current 4,774   4,639 
Lease liabilities, finance lease - current 184   205 
Total current liabilities 16,819   15,087 
Lease liabilities, operating lease 29,974   31,228 
Lease liabilities, finance lease 114   49 
Other liabilities 244   244 
Total liabilities 47,151   46,608 
Stockholders’ equity:   
Common stock 4   4 
Additional paid-in capital 430,027   426,804 
Accumulated deficit (393,887)  (365,970)
Total stockholders’ equity 36,144   60,838 
Total liabilities and stockholders’ equity$83,295  $107,446 

Applied Molecular Transport Inc.
Condensed Statements of Operations
(in thousands, except share and per share amounts)

  Three Months
Ended March 31,
   2023   2022 
Operating expenses:    
Research and development $12,988  $31,239 
General and administrative  6,752   11,337 
Restructuring, impairment, and related charges  8,743    
Total operating expenses  28,483   42,576 
Loss from operations  (28,483)  (42,576)
Interest income, net  579   (3)
Other income (expense), net  (13)  4 
Net loss $(27,917) $(42,575)
Net loss per share, basic and diluted $(0.71) $(1.10)
Weighted-average shares of common stock outstanding, basic and diluted  39,188,397   38,641,365 

Refer to the Company’s applicable SEC filings for previously reported periods.

Investor Relations Contact:
Alexandra Santos
Wheelhouse Life Science Advisors

Media Contact:
Aljanae Reynolds
Wheelhouse Life Science Advisors

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